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MetabolomicsResolvin E1 in follicular fluid acts as a potential biomarker and improves oocyte developmental competence by optimizing cumulus cells

The metabolic profile of follicular fluid (FF) has been investigated to look for biomarkers for oocyte quality. Resolvin E1 (RvE1), a potent pro-resolving mediator, was reported to have protective action in cell function. The study aimed to examine the predictive value of RvE1 for oocyte quality ...

2020-03-26 | MTBLS1488 | MetaboLights
MetabolomicsA single gene mutation underpins metabolic adaptation and acquisition of filamentous competence in the emerging fungal pathogen Candida auris

Filamentous cell growth is a vital property of fungal pathogens. The mechanisms of filamentation in the emerging multidrug-resistant fungal pathogen Candida auris are poorly understood. Here, we show that exposure of C. auris to glycerol triggers a rod-like filamentation-competent (RL-FC) phenoty...

2024-07-04 | MTBLS9053 | MetaboLights
TranscriptomicsPhysiological and molecular characterization of genetic competence in Streptococcus sanguinis
Streptococcus sanguinis is a major component of the oral flora and an important cause of infective endocarditis. The genome sequence of S. sanguinis strain SK36 was recently determined. A number of foreign genes acquired by natural transformation were detected, as well as orthologs of competence gen...
ORGANISM(S): Streptococcus sanguinis 
2011-01-21 | E-GEOD-21619 | biostudies-arrayexpress
TranscriptomicsPeptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence
The induction of genetic competence is a strategy used by bacteria to increase their genetic repertoire under stressful environmental conditions. Recently, Streptococcus pneumoniae has been shown to co-ordinate the uptake of transforming DNA with fratricide via increased expression of the peptide ph...
ORGANISM(S): Streptococcus mutans UA159 
2010-05-29 | E-GEOD-22019 | biostudies-arrayexpress
ProteomicsAcquisition of embryogenic competence during protoplast development of Fagopyrum
Reprogramming in protoplast cultures is a key step for acquiring embryogenic competence by dedifferentiated cells, thus leading to plant regeneration. Therefore, to better understand factors trigging the processes, this work focuses on analysing proteomes, cell wall composition and changes in the ex...
ORGANISM(S): Fagopyrum Esculentum (ncbitaxon:3617) Fagopyrum Tataricum (ncbitaxon:62330) 
MSV000095861 | MassIVE
TranscriptomicsSubpopulation-specific transcriptome analysis of cytometrically sorted Streptococcus mutans cells: Analysis of CSP-mediated intrapopulation diversity
Transcriptional profiling of the competence-stimulating peptide (CSP) response in Streptococcus mutans of FACS-separated subpopulations and mixed cells of a clonal culture. CSP-mediated competence development in S. mutans is a transient and biphasic process since only a subpopulation induces expres...
ORGANISM(S): Streptococcus mutans 
2011-02-01 | E-GEOD-25284 | biostudies-arrayexpress
TranscriptomicsTranscriptome based identification of mouse cumulus cell markers that predict the developmental competence of their enclosed antral oocytes
The cumulus cells (CCs) that envelope antral and ovulated oocytes have been regarded as putative source of non-invasive markers of the oocyte developmental competence and a number of studies have observed a correlation between CCs gene expression, embryo quality and final pregnancy outcome. With the...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-46906 | biostudies-arrayexpress
GenomicsExome sequencing of Congenital Heart Disease families from the Competence Network Berlin
This project aims to study exomes from families and trios with congenital heart disease (CHD). The samples have been collected under the Competence Network - Congenital Heart Defects in Berlin, Germany. The phenotypes are mainly left ventricular outflow obstruction (aortic stenosis, bicuspd aortic v...
EGAS00001000368 | EGA
TranscriptomicsTranscription profiling of Bacillus subtilis wild type and yvcJ strains during the competence transition phase
Competence experiments were carried out in MD medium containing 10.7 g/l K2HPO4, 6 g/l KH2PO4, 1g/l trisodium citrate - 5H2O, 2% (w/v) glucose, 50 mg/l L-Trp, 11 mg/l ferric ammonium citrate, 2.5 g/l potassium aspartate et 3 mM MgS04. Wt and yvcJ strain were cultured in this medium until transition ...
ORGANISM(S): Bacillus subtilis 
2008-12-09 | E-MEXP-1471 | biostudies-arrayexpress
ProteomicsQuantitative phosphoproteomic analysis of Streptococcus pneumoniae reveals that competence modulates protein phosphorylation
Extensive phosphoproteomic studies have revealed that protein phosphorylation on serine, threonine and tyrosine residues is a widespread regulatory post-translational modification in bacteria. In this study, we carried out a biological triplicate of quantitative proteomic and phosphoproteomic analys...
ORGANISM(S): Streptococcus Pneumoniae (ncbitaxon:1313) 
2024-05-23 | MSV000094842 | MassIVE
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