Complement factor c3a

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Transcriptomics (283)
Unknown (139)
Genomics (13)
Proteomics (7)
Metabolomics (5)
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Organisms

Homo sapiens (102)
Mus musculus (99)
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Organisms

Mus musculus (4)
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Repository

biostudies-arrayexpress (285)
geo (5)
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pride (2)
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Tissue

Blood serum (1)
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Disease

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Mass spectrometry assay (3)
Mass spectrometry (2)
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Instrument Platform

Illumina NovaSeq 6000 (9)
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LTQ Orbitrap (2)
Liquid Chromatography MS - positive - reverse-phase (2)
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NA (1)
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Instrument (1)
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Direct infusion MS - negative (1)
Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2010 (56)
2013 (31)
2011 (27)
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2014 (18)
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2007 (14)
2016 (12)
2006 (12)
2005 (12)
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2004 (5)
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2017 (1)
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2019 (1)

CHEBI ID

CHEBI:75008 (2)
CHEBI:25801 (2)
CHEBI:17768 (2)
CHEBI:75016 (2)
CHEBI:75010 (2)
CHEBI:16543 (2)
CHEBI:18237 (2)
CHEBI:22660 (2)
CHEBI:28300 (2)
CHEBI:73506 (2)
CHEBI:73527 (2)
CHEBI:73912 (2)
CHEBI:141447 (1)
CHEBI:141426 (1)
CHEBI:32401 (1)
CHEBI:73806 (1)
CHEBI:141391 (1)
CHEBI:15405 (1)
CHEBI:141390 (1)
CHEBI:141442 (1)
CHEBI:141407 (1)
CHEBI:141406 (1)
CHEBI:141403 (1)
CHEBI:141412 (1)
CHEBI:89110 (1)
CHEBI:89348 (1)
CHEBI:178211 (1)
CHEBI:178210 (1)
CHEBI:178209 (1)
CHEBI:21780 (1)

Metabolite Name

N-Acetylputrescine (2)
Glutamine (2)
Aspartic acid (2)
Quercetin 3-O-glucoside 7-O-rhamnoside (1)
Kaempferol 3-O-glucoside 7-O-rhamnoside (1)
S-Adenosyl methionine (1)
4-[(2E)-3,7-dimethyl-5-oxoocta-2,6-dienyl]-3-methylideneoxolan-2-one (1)
Pyridoxamine-5'-phosphate (1)
4-hydroxy-4-[(E)-3-hydroxybut-1-enyl]-3,5,5-trimethylcyclohex-2-en-1-one (1)
(2E)-11-Hydroxy-2-dodecenoic acid (1)
N-epsilon,N-epsilon,N-epsilon-Trimethyllysine (1)
Alpha-aminopimelic acid (1)
N-Acetyl-L-ornithine (1)
Fenchyl alcohol (1)
Pyridoxol (1)
L-Methionine methylsulfonium (1)
N-(2-Hydroxyethyl)-beta-alanine (1)
Beta-Hydroxynorvaline (1)
3,4-Dimethylaniline (1)
Gamma-Amino-beta-hydroxybutyric acid (1)
(R)-2-Aminobutanoic acid (1)
2',3'-Cyclic Adenosine monophosphate (1)
Alpha-D-Talose (1)
Oxo proline (1)
Stearic acid (18:0) (1)
Phenyl sulfoxide (1)
Oxo-octadecadienoic acid (1)
Octadecyl-oxy-octadecanoic acid (SAHSA) (1)
Octadecanoyloxamide (1)
Nonadecanoic acid (C19:0) (1)

First Public Date

2026 (2)
2023 (1)
2021 (1)
2020 (1)

Study type

Transcription profiling by array (223)
Unknown experiment type (13)
RNA-seq of coding RNA (13)
MicroRNA profiling by array (5)
Comparative genomic hybridization by array (4)
ChIP-seq (4)
ChIP-chip by tiling array (3)
Transcription profiling by tiling array (3)
Other (3)
RNAi profiling by array (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
One-color microarray (1)
ChIP-chip by array (1)
Genotyping by array (1)
Methylation profiling by array (1)
RNA-seq of coding RNA from single cells (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of non coding RNA (1)

Release Date

2010 (60)
2013 (38)
2011 (33)
2008 (28)
2012 (26)
2009 (26)
2014 (22)
2022 (19)
2016 (18)
2015 (17)
2007 (15)
2018 (13)
2026 (12)
2021 (12)
2006 (12)
2005 (12)
2023 (11)
2019 (11)
2020 (10)
2025 (8)
2024 (8)
2017 (7)
2004 (5)
2003 (1)

Lab affiliation

Department of Internal Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria (1)
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, School of Stomatology, The Fourth Military Medical University, Xi’an, Shaanxi 710032, China. (1)

Tags

xref:PubMed:34505065 (1)
xref:PubMed:34031614 (1)
xref:PubMed:36546481 (1)
xref:PubMed:42099652 (1)

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Electroacupuncture at Ll11 and SP10 is associated with alleviation of acute urticaria-like reactions in passive cutaneous anaphylaxis: an exploratory analysis of complement-related proteins and multiscale omics

Background: The lifetime prevalence of acute urticaria is approximately 20%. Although electroacupuncture (EA) has been investigated as an adjunctive treatment for urticaria, the molecular mechanisms underlying these effects remain elusive. Passive cutaneous anaphylaxis (PCA) serves as an experime...

2026-06-03 | MTBLS14327 | MetaboLights

Generation of a C3a-specific monoclonal antibody and immunoapheresis of C3a/C3 and its associates

A high affine murine monoclonal antibody was generated against complement factor C3 and selected for binding to the C3a region to serve as immunoaffinity reagent. Subsequently, a C3a/C3 specific immunoaffinity column was developed and apheresis of C3a/C3 and its associates was performed. A proteomic...

ORGANISM(S): Homo sapiens (Human)

2019-11-27 | PXD009829 | Pride

Regulation of neuronal gene and miRNA expression by the complement protein C1q associated with neuroprotection

Identification of transcriptional profiles stimulated by the complement protein C1q in rat immature neurons associated with the C1q-dependent neuroprotection observed in vitro. Use of the unbiased whole genome microarray approach to identify genes regulated by C1q. Immature neurons grown in vitro fo...

ORGANISM(S): Rattus norvegicus

2011-03-07 | E-GEOD-18860 | biostudies-arrayexpress

Complement Factor H maintains macrophage homeostasis through TRPM7 signaling

PRJNA1170995 | ENA

The complement C3-complement factor D-C3a receptor signalling axis regulates cardiac remodelling in right ventricular failure.

Not available

S-EPMC9478115 | biostudies-literature

Transcription profiling by array of dendritic cells from three different human donors to characterize the impact of differential HIV opsonization on dendritic cell modulation

The aim of this study was to characterize the impact of differential HIV opsonization on DC modulation. DCs are the most potent antigen-presenting cells and among the first cells HIV is attaching to. HIV spontaneously activates the complement system even in the absence of specific antibodies and is ...

ORGANISM(S): Homo sapiens

2015-03-31 | E-MEXP-3706 | biostudies-arrayexpress

Complement C3a and C3a Receptor Activation Mediates Podocyte Injuries in the Mechanism of Primary Membranous Nephropathy.

Not available

S-EPMC9529185 | biostudies-literature

Factor H and related proteins in AMD

Age-related macular degeneration (AMD) is a common form of adult blindness. Risk of developing AMD is strongly linked to genetics, in particular at the Regulators of Complement Activation (RCA) locus on Chr1, which contains 6 genes, Complement Factor H (CFH) and Complement Factor H-related 1-5 (CFHR...

ORGANISM(S): Homo Sapiens

2022-01-18 | PXD023466 | panorama

Complement Factor H maintains macrophage homeostasis through TRPM7 signaling

Factor H (FH) is a critical regulator of the alternative complement pathway preventing uncontrolled complement activation. Its role in mitigating complement-mediated injury is evident in diseases such as dense deposit disease and age related macular degeneration characterized by significant macropha...

ORGANISM(S): Mus musculus

2026-05-05 | GSE279157 | GEO

Complement C3 and Activated Fragment C3a Are Involved in Complement Activation and Anti-Bacterial Immunity.

Not available

S-EPMC8913944 | biostudies-literature

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