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Comparison of endogenous gene expression differences between pterygium and conjunctiva tissues RNA from donor-matched pterygium and conjunctiva tissues obtained from four patients were evaluated for differences in gene expression
ORGANISM(S): Homo sapiens 
To identify dysregulated molecules between pterygium tissues and uninvolved conjunctiva tissues from the same eye, we performed whole genome microarray expression profiling. Total RNA from four pairs of pterygium and uninvolved conjunctiva tissues from the same eye was extracted and used for microa...
ORGANISM(S): Homo sapiens 
Gene Expression profiling of pterygium (benign growth of the conjunctiva). Analysis of conjunctiva and pterygium samples.
ORGANISM(S): Homo sapiens 
Whole human conjunctivae and human corneas were obtained from the National Disease Research Interchange (NDRI, Philadelphia, PA) and processed between 48 - 72 hr of death. No donor details apart from age, sex and cause of death were released. Criteria for inclusion were donor ages between 25 - 65 ye...
ORGANISM(S): Homo sapiens 
To date, there is no specific marker for limbal epithelial stem cells. The identification of a marker that is expressed in the limbal epithelium but not in the cornea or conjunctiva epithelium has been a growing need. To search for limbal-specific marker(s), we performed preferential gene profiling ...
ORGANISM(S): Homo sapiens 
The identification of a marker that is expressed in the conjunctival epithelium but not in the corneal epithelium has been a growing need. A more specific marker of limbal and conjunctival epithelia would be necessary to detect non-corneal epithelial cells on the corneal surface. To search for conju...
ORGANISM(S): Homo sapiens 
The conjunctival epithelium covering the eye consists of two main differentiated cell types: mucus-producing Goblet cells and ‘keratinocytes’ of unknown function. Here, we describe long-term expanding organoids representing human conjunctiva. To check if interleukins may boost secretome expression, ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-11 | PXD043550 | Pride
Collection of biosamples from conjunctiva Metagenome
Gene expression profiling of holoclones from limbus, conjunctiva and oral mucosa
Recently we had discovered a solid cord like structure at the limbus of human eyes, termed as the Limbal Epithelial Crypt (LEC). It arises from the undersurface of the interpalisade rete ridges and extends towards the conjunctiva over the conjunctival stroma. Anatomical and immunohistochemical stud...
ORGANISM(S): Homo sapiens 
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