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MetabolomicsSearching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug, ...
2021-02-08 | MTBLS873 | MetaboLights
ProteomicsSkeletal muscle wt and OXPHOS inhibited 18 months-old mice
TMT sixplex Isobaric Mass Tagging (TAM) analysis was carried out in the CBMSO Protein Chemistry Facility (ProteoRed, PRB3-ISCIII and UAM University, Spain. Chronic skeletal muscle mitochondria dyshomeostasis drives tubular aggregate formation.
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD026771 | Pride
Skeletal muscle soleus gastronecmius mice oxphos tubular agregate myopathy 
ProteomicsSkeletal muscle wt and OXPHOS inhibited 18 months-old mice treated with edaravone
Chronic skeletal muscle mitochondria dyshomeostasis drives tubular aggregate formation. TMT sixplex Isobaric Mass Tagging analysis was carried out in the CBMSO Protein Chemistry Facility (ProteoRed, PRB3-ISCIII and UAM University, Spain.
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD026722 | Pride
Soleus Oxphos Mouse skm Edaravone Tubular agregate myopathy 
MetabolomicsGNPS Fungal extracts from Cenote Tza Itza
Untargeted metabolomics (LC/MS) of fungal extracts (chloroform:methanol) isolated from Cenote Tza Itza in Yucatan, Mexico.
ORGANISM(S): Aspergillus (ncbitaxon:5052) Cladosporium (ncbitaxon:5498) Stachybotrys (ncbitaxon:74721) 
2022-01-17 | MSV000088691 | GNPS
TranscriptomicsMicroarray profiling of polyploid macrophage progeny
To explore how bacterial lipoproteins (i.e. TLR2 ligands) increased macrophage ploidy via mitotic defects, we performed global analysis of cell cycle gene expression changes induced by bacterial lipoproteins. FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of th...
ORGANISM(S): Mus musculus 
2016-10-27 | E-MTAB-5085 | biostudies-arrayexpress
UnknownPOMC AMPKα1 deletion drives male-specific BAT thermogenesis and obesity resistance
Not available
S-SCDT-10_1038-S44319-026-00915-0 | biostudies-other
UnknownAdd-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical Trial.
Not available
S-EPMC12120674 | biostudies-literature
UnknownColombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery - a prospective cohort study.
Not available
S-EPMC11382124 | biostudies-literature
UnknownReducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.
Not available
S-EPMC10364528 | biostudies-literature
UnknownUse of Telemedicine for Postdischarge Assessment of the Surgical Wound: International Cohort Study, and Systematic Review With Meta-analysis.
Not available
S-EPMC10174106 | biostudies-literature
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