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A growing body of evidence in mammalian cells indicates that secreted vesicles can be used to mediate intercellular communication processes by transferring various bioactive molecules, including mRNAs and microRNAs. Based on these findings, we decided to analyze whether T. cruzi-derived extracellula...
ORGANISM(S): Trypanosoma cruzi 
To explore how bacterial lipoproteins (i.e. TLR2 ligands) increased macrophage ploidy via mitotic defects, we performed global analysis of cell cycle gene expression changes induced by bacterial lipoproteins. FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of th...
ORGANISM(S): Mus musculus 
The study reported here is the first characterization of elephant serum proteome in response to TB. These results advance our understanding of elephant immune response to M. tuberculosis and provide potential biomarkers for diagnosis and control of TB in this endangered species.
ORGANISM(S): Elephas maximus maximus 
2022-10-15 | PXD033830 | Pride
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation. Indomethacin, a non-steroidal anti-inflammatory drug, ...
2021-02-08 | MTBLS873 | MetaboLights
8-oxo-7,8-dihydroguanine (8-oxoG) is a common RNA oxidation that has been implicated in carcinogenesis, neurodegeneration, and aging. Some? Many? RNA-binding proteins have shown binding preference for 8-oxoG modified RNA; such binding? can protect cells from oxidative stress. To date, the presence o...
ORGANISM(S): Deinococcus radiodurans ATCC 13939 
2022-07-09 | PXD028866 | Pride
E. histolytica trophozoites (3x105) harvested in exponential growth phase were transferred to 25 cm² cell culture flasks and grown at 37°C for 24 h. Then, parasites were exposed to irradiation in a 254 nm UV-transilluminator (BioDoc-It Imaging System (UVP)) for 30 min at 4°C (Valdés et al., 2014) an...
ORGANISM(S): Entamoeba histolytica HM-1:IMSS-A 
2023-03-11 | PXD033620 | Pride
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