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TranscriptomicsTranscription profiling of hippocampi from scopolamine treated adult rats following stimulation in a spatial memory task
Hippocampal gene expression profiling in scopolamine treated adult rats following stimulation in a spatial memory task
ORGANISM(S): Rattus norvegicus 
2006-12-30 | E-MEXP-920 | biostudies-arrayexpress
UnknownComparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial.
Not available
S-EPMC9418415 | biostudies-literature
UnknownMulticentre, double-blind, crossover trial to identify the Optimal Pathway for TreatIng neurOpathic paiN in Diabetes Mellitus (OPTION-DM): study protocol for a randomised controlled trial.
Not available
S-EPMC6196556 | biostudies-literature
MetabolomicsThe Impact of Ethnicity and Intra-Pancreatic Fat on the Postprandial Metabolome Response to Whey Protein in Overweight Asian Chinese and European Caucasian Women with Prediabetes
The 'Thin on the Outside Fat on the Inside' TOFI_Asia study found Asian Chinese to be more susceptible to Type 2 Diabetes (T2D) compared to European Caucasians matched for gender and body mass index (BMI). This was influenced by degree of visceral adipose deposition and ectopic fat accumulation in k...
2022-10-12 | MTBLS5568 | MetaboLights
TranscriptomicsEffects of exercise on gene expression level in human NK Cells
We tested the hypothesis on the mechanisms responsible for the early control of NK cell function by identifying a discrete set of genes in circulating NK cells that were altered by exercise. Exercise leads to a rapid change in the profile of gene expression in NK cells. Twelve healthy men (20-29 yr ...
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-41914 | biostudies-arrayexpress
TranscriptomicsGlobal expression analysis identified a preferentially NGF-induced transcriptional program regulated by sustained MEK/ERK and AP-1 activation during PC12 differentiation.
Neuronal differentiation of PC12 cells in response to NGF is a prototypical model in which signal duration determines a biological response. Sustained ERK activity induced by NGF, as compared to transient activity induced by EGF, is critical to the differentiation of these cells. To characterize the...
ORGANISM(S): Rattus norvegicus 
2011-11-13 | E-GEOD-33639 | biostudies-arrayexpress
TranscriptomicsEffects of exercise on miRNA expression level in human neutrophils
Exercise leads to a rapid change in the profile of gene expression in circulating neutrophils. We hypothesized that miRNA expression in circulating neutrophils would also be affected by brief exercise. Eleven healthy men (19-30 yr old) performed 10 2-min bouts of cycle ergometer exercise intersperse...
ORGANISM(S): Homo sapiens 
2010-03-31 | E-GEOD-18999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila samples of wild type, aly, can, zaa and zab testes
Drosophila melanogaster males mutant for any meiotic arrest gene have defective spermatogenesis, with cells arresting as primary spermatocytes, and failing to progress to later stages. This phenotype is remarkably similar to meiosis I maturation arrest azoospemia in humans. Drosophila meiotic arrest...
ORGANISM(S): Drosophila melanogaster 
2004-05-07 | E-FLYC-5 | biostudies-arrayexpress
TranscriptomicsEffects of exercise on miRNA expression level in human NK Cells
Exercise leads to a rapid change in the profile of gene expression in NK cells. We hypothesized that microRNA expression in circulating NK cells would also be affected by brief exercise. Eleven healthy men (20-29 yr old) performed 10 2-min bouts of cycle ergometer exercise interspersed with 1-min re...
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-41913 | biostudies-arrayexpress
TranscriptomicssiRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer
Ribosomal protein RPL19 is an integral component of eukaryotic ribosomes and universally involved in protein synthesis. Although consistently stableM-BM- in normal cells, RPL19 transcription is relatively elevated in prostate cancer. Using siRNA, we inhibited RPL19 transcription and demonstrated th...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-26774 | biostudies-arrayexpress
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