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Transcriptional profiling of A549, U2OS, and Nalm6 comparing dexamethason with vehicle control, 3 hour timepoint Two conditions (treated and untreated), three cell types. Biological replicates: 3 treated and 3 vehicle controls for each cell type. Each array is a two-color hyb of treated vs control i...
ORGANISM(S): Homo sapiens 
determine genes regulated by dexamethasone in c3h10t1/2 cells after 90 minutes of treatment compared to vehicle Keywords: treatment comparison microarray c3h10t1/2 cells were treated with vehicle or 1uM dexamethasone for 90 minutes (3 biological replicates of each) RNA samples were isolated from RNe...
ORGANISM(S): Mus musculus 
Methylation is a common post-translational modification of lysine and arginine in eukaryotic proteins. To date, these methylomes are best characterised in model organisms and higher eukaryotes. Herein, we integrated bioinformatics, proteomics and high-content drug-screening to comprehensively explor...
ORGANISM(S): Giardia lamblia ATCC 50803 
2020-08-07 | PXD016813 | Pride
We explored differential protein expression (DEPs) during sublethal exposures of HKMT inhibitors (BIX-01294 = 10uM (B), Chaetocin = 20uM (C)) in log-phase (growth; TY) and encystation (differentiation; EC) at 8 and 24 hours relative to DMSO controls (D). In total, 18,527 peptides from 1,981 proteins...
ORGANISM(S): Giardia lamblia ATCC 50803 
2020-08-04 | PXD016747 | Pride
Phylogenetic analysis of the extinct dire wolf was carried out to explore the relationship this species had with other Canids.
ORGANISM(S): Canis dirus 
2020-11-02 | PXD021930 | Pride
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