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TranscriptomicsGenome-wide analysis of microRNA-22 responsive gene expression in lung antigen presenting cells in response to chronic nanoparticulate carbon black exposure
Analysis of lung CD11c+ antigen presenting cells (APCs) isolated from wildtype or Mir22-/- mice exposed to nanoparticulate carbon black (nCB) for one month. MiR-22 plays important roles in nCB induced experimental emphysema through regulating APC activation. Results provide insight into the biologi...
ORGANISM(S): Mus musculus 
2015-09-05 | E-GEOD-72734 | biostudies-arrayexpress
MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
TranscriptomicsBone marrow-derived macrophages express distinct transcriptional programs when activated by LPS, IFN-gamma and PAO.
mRNA microarray analysis of bone marrow derived macrophages treated under four conditions, including Naïve (N). Bone marrow derived macrophages (BMDM) were derived from the bone marrow of mice and cultured in the presence of PAO, IFN-gamma, or lipopolysaccharide (LPS). Profiled groups include Naive...
ORGANISM(S): Mus musculus 
2013-08-08 | E-GEOD-48609 | biostudies-arrayexpress
TranscriptomicsA gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-27597 | biostudies-arrayexpress
UnknownChronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.
Not available
S-EPMC11601417 | biostudies-literature
UnknownHigh-affinity CD16A polymorphism associated with reduced risk ofsevere COVID-19.
Not available
S-EPMC12306582 | biostudies-literature
UnknownType 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.
Not available
S-EPMC12284355 | biostudies-literature
UnknownHost-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.
Not available
S-EPMC11931290 | biostudies-literature
UnknownHost-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Not available
S-EPMC11723965 | biostudies-literature
UnknownPhenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
Not available
S-EPMC9359694 | biostudies-literature
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