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TranscriptomicsTranscription profiling of lymphocytes from allergic and tolerant patients after stimulation with p-phenylenediamine and Bandrowskis base
Measurement of cytokine secretion and gene expression changes from allergic and tolerant
patient lymphocytes stimulated with p-phenylenediamine and Bandrowski's base
ORGANISM(S): Homo sapiens 
2009-01-01 | E-MEXP-1812 | biostudies-arrayexpress
TranscriptomicsTranscription repression of miR-221 leads to p27 expression in PEL
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-12-05 | E-GEOD-18439 | biostudies-arrayexpress
TranscriptomicsSex of Blood
Blood samples were taken at 1:00 pm +/- 1 h (Potassium-EDTA-monovettes, Sarstedt, Numbrecht, Germany) to control for circadian influences on gene expression. Blood was taken from normal male controls, normal female controls as well as different patients with disorders of sex development leading to a...
ORGANISM(S): Homo sapiens 
2009-07-13 | E-GEOD-11235 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed human and viral miRNAs across a panel of B-cell lines, including primary effusion lymphomas
To identify differentially expressed human and viral miRNAs across a panel of B-cell lines, including several primary effusion lymphomas (PEL). Gammaherpesvirus and host cell microRNAs (miRNAs) together modulate gene expression in normal and malignant cells. Using microRNA microarrays, we determined...
ORGANISM(S): Homo sapiens 
2015-12-05 | E-GEOD-18437 | biostudies-arrayexpress
TranscriptomicsOver-expression of hsa-miR-221 in JSC1 cells and identification of miRNA targets expressed in a panel of B-cell lines
1) To identify changes in gene expression upon over-expression of hsa-miR-221 in JSC1 cells. 2) To identify human miRNA targets expressed in a panel of B-cell lines. Gammaherpesvirus and host cell microRNAs (miRNAs) together modulate gene expression in normal and malignant cells. Using microRNA micr...
ORGANISM(S): Homo sapiens 
2015-12-05 | E-GEOD-18438 | biostudies-arrayexpress
GenomicsEpigenomic landscapes of human inflammation associated macrophages [ChIP-seq]
We previously demonstrated by genomic and bioinformatical approaches that human macrophage (MΦ) activation is best described by a spectrum model (Xue et al, Immunity, 2014). MΦ integrate exogenous input signals on transcriptional level in a unique fashion to generate specific functional programs, ...
ORGANISM(S): Homo sapiens 
2016-02-28 | E-GEOD-66594 | biostudies-arrayexpress
GenomicsBase-pair level resolution of the Nasonia vitripennis methylome
The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns reported...
ORGANISM(S): Nasonia vitripennis 
2013-08-27 | E-GEOD-43423 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs in B cells (RNA-Seq)
Using RNA sequencing and de novo transcript assembly, we identified 4516 lncRNAs expressed in 8 different stages of B cell development and activation. Chromatin immuno-precipitation sequencing was used to classify a substantial fraction (38%) of these lncRNAs as enhancer-associated or promoter-assoc...
ORGANISM(S): Mus musculus 
2016-07-15 | E-GEOD-72018 | biostudies-arrayexpress
TranscriptomicsLATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-63538 | biostudies-arrayexpress
Transcriptomics18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers.
Fluorine-18-fluoro-2-deoxy-D-glucose (FDG) is widely used as positron-emission-tomography (PET) radiotracer for the detection and staging of human cancer. Tumor uptake of FDG varies substantially between different cancer types and between patients with the same tumor type. The molecular basis for th...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-21217 | biostudies-arrayexpress
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