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MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
MetabolomicsMultiparous and Primiparous Simmental Dairy Cows
Not available
ORGANISM(S): Bos taurus 
ST001349 | MetabolomicsWorkbench
MetabolomicsL-Citrulline and L-arginine regulate the reproductive performance of young and adult cows through distinct metabolic pathways and the shared pyrimidine metabolic pathway respectively

(Background)To investigate the impact of L-arginine (L-Arg) and L-citrulline (L-Cit) on cow reproductive performance.(Methods) 90 healthy, age-matched Simmental cows were randomly assigned to three groups: control, L-Arg, and L-Cit, with 30 cows per group. Estrus synchronization was performed, an...

2025-07-05 | MTBLS12682 | MetaboLights
MetabolomicsAltered Fecal Microbiome and Correlations of the Metabolome with Plasma Metabolites in Dairy Cows with Left Displaced Abomasum

Left displaced abomasum (LDA) in postpartum dairy cows contributes to significant economic losses. LDA is characterized by excessive lipolysis and insulin resistance. Although gut dysbiosis is implicated, little is known about the role of the gut microbiota in the abnormal metabolic processes of ...

2022-08-17 | MTBLS2441 | MetaboLights
MetabolomicsColostrum metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of colostrum samples collected at the first milking after calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromi...
2026-09-26 | MTBLS15562 | MetaboLights
MetabolomicsMaternal plasma metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of maternal plasma collected on the day of calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propionate o...
2026-09-26 | MTBLS15538 | MetaboLights
MetabolomicsRectal-content metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of rectal-content samples collected on the day of calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propi...
2026-09-26 | MTBLS15543 | MetaboLights
MetabolomicsRumen-fluid metabolomic profiling of periparturient dairy cows supplemented with high-dose chromium propionate before calving
This study contains untargeted LC-MS/MS metabolomic profiles of rumen-fluid samples collected on the day of calving from Holstein dairy cows in the control and high-dose chromium propionate supplementation groups. Cows received either a basal total mixed ration without supplemental chromium propiona...
2026-09-26 | MTBLS15553 | MetaboLights
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