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TranscriptomicsTranscriptomic analysis of fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line
Transcriptomic analysis using qRT-PCR was performed on fresh frozen clear-cell renal cell carcinoma tissues treated with VEGFR-TKIs in first line (n=109). The transcriptomic data from this experiment were analyzed together with miRNA sequencing data from FFPE samples from the same tumor (E-MTAB-1058...
ORGANISM(S): Homo sapiens 
2021-06-07 | E-MTAB-10592 | biostudies-arrayexpress
ProteomicsDecoupling of mRNA and protein expression in aging brains reveals the age-dependent adaptation of specific gene subsets
During aging, changes in gene expression are associated with decline in physical and cognitive abilities. Here, we investigated the connection between changes of mRNA and protein expression in the brain by comparing the transcriptome and proteome of the mouse cortex during aging. Our transcriptomic ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD038179 | Pride
Proteomics Brain Cortex Mouse Aging Mrna 
UnknownSleep characteristics and recurrence in platinum-sensitive ovarian cancer survivors: A prospective cohort study.
Not available
S-EPMC11567917 | biostudies-literature
TranscriptomicsMethylation profiling by array of 108 clear cell renal cell carcinoma
A Cartes d'Identite des Tumeurs (CIT) project from the French Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment wi...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-MTAB-3274 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Clear cell renal carcinoma
Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. Our aim was to identify molecular markers associated with outcome in m-ccRCC patients treated with sunitinib. A Cartes d’Ident...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3267 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptomics of neonatal mouse anterior pituitary in steady-state conditions and after transgenically inflicted local damage
The mouse pituitary gland undergoes vivid maturation immediately after birth. During this process, the local stem cell compartment shows signs of activation including elevated abundance and expression of stemness pathways when compared to adult pituitary stem cells. In addition, we found that the ne...
ORGANISM(S): Mus musculus 
2022-07-11 | E-MTAB-11337 | biostudies-arrayexpress
ProteomicsRBM15 CoIP in mouse Embryonic Stem cells
RBM15 interactome has been determined in mouse Embryonic Stem cells. The cells express inducible emGFP-PreScission-RBM15 alongside with inducible Xist RNA.
ORGANISM(S): Mus musculus (Mouse) 
2020-02-07 | PXD017348 | Pride
Rbm15 Mesc 
TranscriptomicsSingle-cell transcriptional profiling of young-adult and aging (middle-aged) mouse anterior pituitary in steady-state conditions and after transgenically inflicted local damage
Adult pituitary stem cells (SC) are mainly dormant, yet in the case of damage the resident SC compartment shows swift activation. More in particular, following diphtheria toxin (DT)-triggered endocrine cell-ablation injury in the GHCre/iDTR mouse model (expressing the Cre recombinase under control o...
ORGANISM(S): Mus musculus 
2021-06-15 | E-MTAB-10021 | biostudies-arrayexpress
TranscriptomicsGenotyping by array of 108 clear cell renal cell carcinoma
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment with targeted tyrosine kinase inhibitors (TKIs) is a challenge. ...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-MTAB-3269 | biostudies-arrayexpress
Transcriptomicsm6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome
N6-methyladenosine (m6A) is a widespread reversible chemical modification of RNAs, implicated in many aspects of RNA metabolism. Little quantitative information exists as to either how many transcript copies of particular genes are m6A modified (“m6A levels”), or the relationship of m6A modifica...
ORGANISM(S): Homo sapiens 
2016-06-24 | E-GEOD-66086 | biostudies-arrayexpress
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