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RBM15 interactome has been determined in mouse Embryonic Stem cells. The cells express inducible emGFP-PreScission-RBM15 alongside with inducible Xist RNA.
ORGANISM(S): Mus musculus (Mouse) 
2020-02-07 | PXD017348 | Pride
Rbm15-irCLIP-seq
RBM15-mediated Metabolic Reprogramming Boosts Immune Response in Colorectal Cancer
we performed infrared crosslinking immunoprecipitation followed by sequencing (irCLIP-seq) (Zarnegar et al., 2016) for Rbm15 to directly map its binding sites on RNA. As a principle of concept, the cells were engineered to simultaneously express emGFP-Rbm15 and Xist RNA together, as Rbm15 strongly i...
ORGANISM(S): Mus musculus 
2020-09-15 | GSE154708 | GEO
Immune checkpoint blockade (ICB) offers therapeutic options for patients with advanced colorectal cancer; however, only a subset of patients with microsatellite instability-high (MSI-H) tumors respond to treatment. Therefore, strategies to enhance immunotherapy sensitivity are urgently needed. In th...
ORGANISM(S): Homo sapiens 
2025-04-15 | GSE279678 | GEO
The conserved mRNA nuclear export receptor NXF1 (Mex67 in yeast) assembles with messenger ribonucleoproteins (mRNP) in the nucleus and guides them through the nuclear pore complex (NPC) into the cytoplasm. The DEAD-box RNA helicase Dbp5 is essential for nuclear export of mRNA and is thought to disso...
ORGANISM(S): Mus musculus 
2008-06-18 | GSE11785 | GEO
RBM15, an RNA binding protein, determines cell-fate specification of many tissues including blood. We demonstrate that RBM15 is methylated by protein arginine methyltransferase 1 (PRMT1) at residue R578 leading to its degradation via ubiquitylation by an E3 ligase (CNOT4). Overexpression of PRMT1 in...
ORGANISM(S): Homo sapiens 
2015-11-17 | GSE73893 | GEO
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