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TranscriptomicsRNA-seq analysis of C. elegans CPEB homolog mutants.
Comparative transcriptomics study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.
ORGANISM(S): Caenorhabditis elegans 
2017-08-03 | E-MTAB-4720 | biostudies-arrayexpress
ProteomicsAcute synthesis of CPEB is required for plasticity of visual avoidance behavior in Xenopus
Neural plasticity requires protein synthesis, but the identity of newly synthesized proteins generated in response to plasticity-inducing stimuli remains unclear. We used in vivo bio-orthogonal noncanonical amino acid tagging (BONCAT) with the methionine analog azidohomoalanine (AHA) combined with t...
ORGANISM(S): Xenopus Laevis (ncbitaxon:8355) 
2018-01-11 | MSV000081914 | MassIVE
ProteomicsSpike-in SILAC MS of C. elegans CPEB homolog mutants.
Comparative proteomic study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.
ORGANISM(S): Caenorhabditis elegans 
2017-08-02 | PXD004104 | Pride
Hilic C. elegans Cpeb proteins Maxquant Spike-in silac Lc-ms/ms 
TranscriptomicsCPEB inducible knock-down in a H.D. Myz cell line
Messenger RNA stability, localization, and translation are largely determined by sequences in their 3M-bM-^@M-2 untranslated regions (3M-bM-^@M-^YUTRs), which recruit regulatory proteins and RNAs. More than half of the mammalian genes generate multiple mRNA isoforms differing in their 3M-bM-^@M-2UTR...
ORGANISM(S): Homo sapiens 
2013-02-25 | E-GEOD-32440 | biostudies-arrayexpress
TranscriptomicsRNA-binding profiles of Drosophila CPEB proteins Orb and Orb2
Localized protein translation is critical in many biological contexts, particularly in highly polarized cells, such as neurons, to regulate gene expression in a spatiotemporal manner. The cytoplasmic polyadenylation element-binding (CPEB) family of RNA-binding proteins has emerged as a key regulator...
ORGANISM(S): Drosophila melanogaster 
2016-10-30 | GSE59611 | GEO
ProteomicsComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expressionComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expression
Background: The vertebrate CPEB-family of RNA-binding proteins promote translational repression or activation of their target mRNAs, which harbor cytoplasmic polyadenylation elements (CPEs) in their 3’ UTRs, through cytoplasmic changes in their poly(A) tail lengths. However, their regulation(s) and ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-05 | PXD030480 | Pride
Mrna translation Deadenylation Cpeb Phosphorylation Ccr4-not complex Phase-separation Bioid 3’utr 
ProteomicsComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expression
Background: The vertebrate CPEB-family of RNA-binding proteins promote translational repression or activation of their target mRNAs, which harbor cytoplasmic polyadenylation elements (CPEs) in their 3’ UTRs, through cytoplasmic changes in their poly(A) tail lengths. However, their regulation(s) and ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-05 | PXD033349 | Pride
Mrna translation Deadenylation Cpeb Phosphorylation Ccr4-not complex Phase-separation Bioid 3’utr 
ProteomicsComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expression
Background: The vertebrate CPEB-family of RNA-binding proteins promote translational repression or activation of their target mRNAs, which harbor cytoplasmic polyadenylation elements (CPEs) in their 3’ UTRs, through cytoplasmic changes in their poly(A) tail lengths. However, their regulation(s) and ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-05 | PXD030419 | Pride
Mrna translation Deadenylation Cpeb Phosphorylation Ccr4-not complex Phase-separation Bioid 3’utr 
UnknownRNA-binding profiles of Drosophila CPEB proteins Orb and Orb2.
Not available
S-EPMC5111685 | biostudies-literature
TranscriptomicsRIP-Chip analysis of the C. elegans FOG-1 and FOG-3 proteins
FOG-1/CPEB and FOG-3/Tob are the terminal regulators of the sex determination in C. elegans germ cells. CPEB and Tob proteins are both translational regulators. To investigate how FOG-1 and FOG-3 regulate germ cell sex determination we sought to identify the target mRNAs. We used transgenic epito...
ORGANISM(S): Caenorhabditis elegans 
2015-12-14 | E-GEOD-73070 | biostudies-arrayexpress
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