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ProteomicsA Novel Method for Isolating Whole Protein from Human Cranial Bone
The presence of the extracellular matrix within human bone limits the applicability of conventional protocols for protein extraction. As a result, complete and accurate characterization of human bone proteome is yet to be performed, and as a result, several bone-related diseases such as craniosynost...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080697 | MassIVE
ProteomicsA Novel Method for Isolating Whole Protein from Human Cranial Bone
The presence of the extracellular matrix within human bone limits the applicability of conventional protocols for protein extraction. As a result, complete and accurate characterization of human bone proteome is yet to be performed, and as a result, several bone-related diseases such as craniosynost...
ORGANISM(S): Homo sapiens (Human) 
2016-10-05 | PXD003215 | Pride
Protein Extraction Method Cranial bone Q-exactive Human Proteome Whole protein 
TranscriptomicsCharacterization of distinct classes of differential gene expression in osteoblast cultures from non-syndromic craniosynostosis bone
We report on explant osteoblast cultures from human patients, demonstrating that there are at least three sub-types of non-syndromic craniosynostosis defined by similarity of gene expression profiles. Osteoblast growth in culture, 23 craniosynostosis skull samples (7 metopic; 8 coronal; 3 lambdoid; ...
ORGANISM(S): Homo sapiens 
2014-07-16 | E-GEOD-55282 | biostudies-arrayexpress
ProteomicsIdentification of differentially expressed proteins between fused and open sutures in sagittal nonsyndromic craniosynostosis during suture development by quantitative proteomic analysis
Craniosynostosis (CS) is a common birth defect due to the premature fusion of one or more cranial sutures. It manifests with abnormal skull shape and is associated with significant morbidities such as increased intracranial pressure, vision problems, and learning disabilities. Nonsyndromic craniosyn...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-20 | MSV000085130 | MassIVE
TranscriptomicsIdentification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors
This SuperSeries is composed of the following subset Series: GSE9603: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on NIA 15k microarray GSE9619: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on ...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-9620 | biostudies-arrayexpress
UnknownChondrocyte Tsc1 controls cranial base bone development by restraining the premature differentiation of synchondroses.
Not available
S-EPMC8543925 | biostudies-literature
TranscriptomicsGene Expression Changes Between Patent and Fused Cranial Sutures in a Nonsyndromic Craniosynostosis Population
Assaying gene expression in sutural bone fragments from patients diagnosed with non-syndromic craniosynostosis. Sutural fragments were collected from both the fused and patent cranial suture of infants during cranial vault reconstruction. Gene expression was compared between the patent and fused s...
ORGANISM(S): Homo sapiens 
2013-09-12 | E-GEOD-50796 | biostudies-arrayexpress
GenomicsImpact of cranial bone-derived mesenchymal stem cell transplantation for functional recovery in experimental spinal cord injury
Impact of cranial bone-derived mesenchymal stem cell transplantation for functional recovery in experimental spinal cord injury
PRJNA898612 | ENA
UnknownGαs signaling controls intramembranous ossification during cranial bone development by regulating both Hedgehog and Wnt/β-catenin signaling.
Not available
S-EPMC6242855 | biostudies-literature
UnknownData-driven Normative Reference of Pediatric Cranial Bone Development.
Not available
S-EPMC9377678 | biostudies-literature
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