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TranscriptomicsGenomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns
CHD7 is a member of the chromodomain helicase DNA binding domain family of ATP-dependent chromatin remodeling enzymes. De novo mutation of the CHD7 gene is a major cause of CHARGE syndrome, a genetic disease characterized by a complex constellation of birth defects. To gain insight to the function...
ORGANISM(S): Mus musculus 
2009-01-22 | E-GEOD-14460 | biostudies-arrayexpress
GenomicsA Genome Wide Scan of Lung Cancer and Smoking

The majority of cases of lung cancer are the culmination of a dynamic process that begins with smoking initiation, proceeds through dependency and smoking persistence, continues with lung cancer development and ends with progression to disseminated disease or response to therapy and survival. We ...

phs000093.v2.p2 | EGA
UnknownTargeting DNA Damage Response and Replication Stress in Pancreatic Cancer.
Not available
S-EPMC8167930 | biostudies-literature
UnknownProstate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916.
Not available
S-EPMC2684851 | biostudies-literature
GenomicsCHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression.
Gene expression changes were measured between mouse ES cells of three genotypes: WT Chd7, Heterzygous Chd7 Null, Homozygous Chd7 Null. The hypothesis being tested was that CHD7, a chromatin remodeling protein, functions as a transcriptional regulator. This experiment was performed to detect gene t...
ORGANISM(S): Mus musculus 
2010-06-15 | E-GEOD-22341 | biostudies-arrayexpress
UnknownEffects of digital chatbot on gender attitudes and exposure to intimate partner violence among young women in South Africa.
Not available
S-EPMC10578594 | biostudies-literature
GenomicsFoxA1 specifies unique androgen and glucocorticoid receptor binding events in prostate cancer cells (HTS)
We report the androgen receptor recruitment to the chromatin of androgen responsive prostate cancer cell lines, LNCaP-1F5 and VCaP in response to physiological androgen 5a-dihydrotestosterone (DHT) using ChIP-sequencing. We compare the AR recruitment by DHT to that by partial agonist/antagonist cypr...
ORGANISM(S): Homo sapiens 
2013-02-05 | E-GEOD-39879 | biostudies-arrayexpress
TranscriptomicsNHGRI Menin ChIP-Chip
Multiple endocrine neoplasia type I (MEN1) is a familial cancer syndrome characterized primarily by tumors of multiple endocrine glands. The gene for MEN1 encodes a ubiquitously expressed tumor suppressor protein called menin. Menin was recently shown to interact with several components of a trithor...
ORGANISM(S): Homo sapiens 
2006-07-24 | E-GEOD-5357 | biostudies-arrayexpress
UnknownProteomic and metabolic profiling reveals <i>APOE4</i>-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis.
Not available
S-EPMC12262718 | biostudies-literature
UnknownEffect of vitamin D and inhaled corticosteroid treatment on lung function in children.
Not available
S-EPMC3480528 | biostudies-literature
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