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ProteomicsCombining quantitative proteomics and interactomics for a deeper insight into molecular differences between human cell lines
Cellular functional pathways have evolved through selection based on fitness benefits conferred through protein intra- and inter-molecular interactions that comprise all protein conformational features and protein-protein interactions, collectively referred to as the interactome. While the interact...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-17 | PXD055943 | Pride
Mouse Cross-linking Mitochondria 
UnknownAnna Karenina and the subgingival microbiome associated with periodontitis.
Not available
S-EPMC8091542 | biostudies-literature
TranscriptomicsCluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy
Overall, the widely disparate transcriptomes identified prior to RT among the three clusters support the notion that at least some of the inter-individual heterogeneity in propensity for RT-induced myofiber hypertrophy is likely pre-determined. Baseline comparisons of skeletal muscle transcript prof...
ORGANISM(S): Homo sapiens 
2013-05-24 | E-GEOD-42507 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human and mouse keratinocytes infected with AD and Ad-NotchIC viruses reveals cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial self-renewal. Here we show that p63 expression is suppressed by Notch1 a...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5229 | biostudies-arrayexpress
TranscriptomicsMultiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis [small RNA-seq]
We have used an integrative high content analysis approach to identify the specific miRNAs implicated in EGF signaling in HeLa cells as potential mediators of cancer mediated functions. We have used microarray and deep-sequencing technologies in order to obtain a global view of the EGF miRNA transcr...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-41359 | biostudies-arrayexpress
TranscriptomicsMultiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis [Agilent]
We have used an integrative high content analysis approach to identify the specific miRNAs implicated in EGF signaling in HeLa cells as potential mediators of cancer mediated functions. We have used microarray and deep-sequencing technologies in order to obtain a global view of the EGF miRNA transcr...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-41181 | biostudies-arrayexpress
TranscriptomicsMultiple platform assessment and isomir analysis of the EGF dependent microRNA-ome by microarray and deep sequencing analysis [Exiqon]
We have used an integrative high content analysis approach to identify the specific miRNAs implicated in EGF signaling in HeLa cells as potential mediators of cancer mediated functions. We have used microarray and deep-sequencing technologies in order to obtain a global view of the EGF miRNA transcr...
ORGANISM(S): Homo sapiens 
2013-06-11 | E-GEOD-41225 | biostudies-arrayexpress
TranscriptomicsResponse of Methicillin-resistant Staphylococcus aureus to Amicoumacin A
Methicillin resistant Staphylococcus aureus (MRSA) infection is becoming refractory to existing antibiotic therapy owing to the inherent ability of S. aureus to develop rapid resistance and is considered a major threat to public health. We found that a natural isolate of Bacillus pumilus from the C...
ORGANISM(S): Staphylococcus aureus 
2012-07-30 | E-GEOD-31342 | biostudies-arrayexpress
ProteomicsInteractome quantitation reveals non-energetic mitochondrial roles in cell type specialization in murine kidney
Evolution of multicellular life forms has involved adaptation of organs that consist of multiple cell types, each with unique functional properties that as a collection, achieve complex organ function. Since each cell type is adapted to deliver specific functionality within the context of an organ,...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-29 | PXD062841 | Pride
Mouse Kidney Xl-ms Mitochondria 
ProteomicsInteractome quantitation reveals non-energetic mitochondrial roles in cell type specialization in murine kidney
Evolution of multicellular life forms has involved adaptation of organs that consist of multiple cell types, each with unique functional properties that as a collection, achieve complex organ function. Since each cell type is adapted to deliver specific functionality within the context of an organ,...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-29 | PXD062836 | Pride
Dia Mouse Kidney Xl-ms Mitochondria 
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