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ProteomicsPlant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages
A growing body of evidence supports the importance of T cell responses to protect against severe influenza, promote viral clearance and ensure long-term immunity. Plant-derived virus-like particle (VLP) vaccines bearing influenza hemagglutinin (HA) have been shown to elicit strong humoral and CD4+ T...
ORGANISM(S): Homo sapiens (Human) 
2019-05-28 | PXD010519 | Pride
Influenza Cell-mediated immunity Cross-presentation Major histocompatibility complex class i Human monocyte-derived macrophage High-resolution mass spectrometry Plant-derived vaccine Virus-like particle 
TranscriptomicsCross-presenting CD103+ dendritic cells are protected from influenza virus infection
CD8+ cytotoxic T cells are critical for viral clearance from the lungs upon influenza virus infection. The contribution of cross-presentation to the induction of anti-viral cytotoxic T cells remains debated. Here, we used a recombinant influenza virus expressing a NS1-GFP reporter gene to visualize ...
ORGANISM(S): Mus musculus 
2013-06-19 | E-GEOD-38838 | biostudies-arrayexpress
UnknownKIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation.
Not available
S-EPMC5501362 | biostudies-literature
TranscriptomicsArray-based cross-species hybridization between genera of Rhabditidae (Nematoda)
The objective of this work was to determine the effectiveness of cross-hybridization of gDNA from five native soil nematodes to an Affymetrix Caenorhabditis elegans tiling array. Cross-hybridization experiments using C. briggsae, for which genome information is available, allowed hybridisation inten...
ORGANISM(S): Caenorhabditis briggsae 
2010-08-17 | E-GEOD-23667 | biostudies-arrayexpress
TranscriptomicsIRF4, a master transcription factor, regulates genes involved in BCR signaling, antigen processing and presentation, and GC development [ChIP-chip]
Interferon regulatory factor 4 (IRF4) is a master transcription factor required for the maturation of germinal center B cells that eventually develop into antibody secreting plasma cells and memory B cells. IRF4-deficient mice exhibit a profound reduction in serum immunoglobulin levels. In spite of...
ORGANISM(S): Homo sapiens 
2015-12-15 | E-GEOD-64268 | biostudies-arrayexpress
TranscriptomicsEvaluation of RNA-Seq with External RNA Control Consortium (ERCC) spike-ins
This SuperSeries is composed of the following subset Series: GSE20555: RNA-Seq on libraries made from serial dilutions of Drosophila melanogaster S2 cell mRNA and ERCC external RNA controls GSE20579: RNA-Seq on libraries made from ERCC external RNA controls, and a mixture of D. melanogaster S2 cell ...
ORGANISM(S): synthetic construct 
2010-04-18 | E-GEOD-20580 | biostudies-arrayexpress
UnknownIntracranial aneurysm location: potential influencing factor in ruptures with internal carotid artery occlusion
Not available
S-EPMC12345041 | biostudies-literature
TranscriptomicsChIP-chip profiling of SsrB in Salmonella enterica sv. Typhimurium
We performed chromatin immunoprecipitation on microarray (ChIP-chip) transcriptional profiling of the SsrB regulator of Salmonella enterica Typhimurium to better characterize its regulon and to identify the DNA-recognition element coordinating its specific interaction at cis-regulatory sites. SsrB,...
ORGANISM(S): Salmonella typhimurium SL1344 
2010-02-08 | E-GEOD-20192 | biostudies-arrayexpress
UnknownVentilatory threshold may be a more specific measure of aerobic capacity than peak oxygen consumption rate in persons with stroke.
Not available
S-EPMC5588902 | biostudies-literature
UnknownKnowledge, Attitude, and Practice of Medication Use During Pregnancy: A Cross-Sectional Study in Western Uganda.
Not available
S-EPMC11985899 | biostudies-literature
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