Sort   by:  
 Page size 
ProteomicsProgress Toward Proteome-Wide Photo-Crosslinking to Enable Residue-Level Visualization of Protein Structure and Networks in vivo
Crosslinking mass spectrometry (XL-MS) is emerging as a method at the crossroads of structural and cellular biology, uniquely capable of identifying protein-protein interactions with residue-level resolution and on the proteome-wide scale. With the development of crosslinkers that can form linkages ...
ORGANISM(S): Escherichia coli 
2023-06-27 | PXD041148 | Pride
Diazirines Cleavable cross-linkers Proteomics Quinary interactions Nhs-carbamate. Photo-crosslinking Protein interaction networks 
TranscriptomicsExpression data from MSC-treated monocytes
Chronic inflammation leading to pro-inflammatory macrophage infiltration contributes to the pathogenesis of type 2 diabetes and subsequently the development of diabetic nephropathy. Mesenchymal stem cells (MSCs) possess unique immunomodulatory and cytoprotective properties making them an ideal candi...
ORGANISM(S): Homo sapiens 
2015-11-10 | E-GEOD-65561 | biostudies-arrayexpress
ProteomicsStructural Basis of Kinesin-1 Autoinhibition and Its Control of Microtubule-Based Motility
Kinesin-1 is the first identified microtubule-based motor protein that drives anterograde intracellular transport of diverse cargoes in eukaryotic cells. Defects in kinesin-1 activity have been implicated in various human neurological disorders and intracellular pathogens such as bacteria and viruse...
ORGANISM(S): Escherichia coli 
2026-06-03 | PXD073177 | Pride
Kinesin-1 Structure Kinesin Kif5b Plus-end directed Microtubule motor Cryo-em Motor protein 
ProteomicsCryo-EM structures of the Plant Augmin reveal its intertwined coiled-coil assembly, antiparallel dimerization and NEDD1 binding mechanisms
Microtubule (MT) branch nucleation is fundamental for building parallel MT networks in eukaryotic cells. In plants and metazoans, MT branch nucleation requires Augmin and NEDD1 proteins which bind along MTs and then recruit and activate the gamma-tubulin ring complex (g-TuRC). Augmin is a fork-shap...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-10-31 | PXD065516 | Pride
Microtubule Augmin G-turc Xl-ms Nedd1 
TranscriptomicsTranscription profiling of fission yeast wild type and zinc regulatory null mutant grown in low zinc growth conditions
Transcription profile of low zinc growth condition in zinc regulatory null mutant
ORGANISM(S): Schizosaccharomyces pombe 
2008-02-22 | E-TABM-427 | biostudies-arrayexpress
UnknownPostmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias.
Not available
S-EPMC12857747 | biostudies-literature
UnknownFactors associated with COVID-19 stigma during the onset of the global pandemic in India: A cross-sectional study.
Not available
S-EPMC9615248 | biostudies-literature
UnknownModifications to the gut microbiome alter bone matrix proteomics and fracture toughness at the cellular scale.
Not available
S-EPMC12697349 | biostudies-literature
TranscriptomicsTranscription profiling of fission yeast timecourse mcs6 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast timecourse pmh1 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-191 | biostudies-arrayexpress
Sort   by:  
 Page size