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TranscriptomicsKinesin-associated RNA: RNA co-immunoprecipitated with Kinesin IP vs RNA from Aplysia CNS
Whole genome transcriptional profiling is used to identify ESTs found in RNA co-immunoprecipitated from Aplysia CNS with antibodies against Aplysia Kinesin Heavy Chain (ApKHC) RNA derived from Aplysia CNS served as control in the opposite channel. Custom Aplysia EST array to probe the samples was de...
ORGANISM(S): Aplysia californica 
2013-04-26 | E-GEOD-30386 | biostudies-arrayexpress
ProteomicsStructural Basis of Kinesin-1 Autoinhibition and Its Control of Microtubule-Based Motility
Kinesin-1 is the first identified microtubule-based motor protein that drives anterograde intracellular transport of diverse cargoes in eukaryotic cells. Defects in kinesin-1 activity have been implicated in various human neurological disorders and intracellular pathogens such as bacteria and viruse...
ORGANISM(S): Escherichia coli 
2026-06-03 | PXD073177 | Pride
Kinesin-1 Structure Kinesin Kif5b Plus-end directed Microtubule motor Cryo-em Motor protein 
TranscriptomicsToward synaptic transcriptomes: Direct sequencing and identification of RNAs actively transported by the kinesin complex from the cell body to synapses in Aplysia neurons
Specific mRNAs are transported from the cell body to synapses where their translation can modify communication of pre-existing synapses and induce formation of new synaptic connections in response to learning. Little is known, however, about the identity of the RNAs that are actively transported an...
ORGANISM(S): Aplysia californica 
2013-04-24 | E-GEOD-30440 | biostudies-arrayexpress
TranscriptomicsAplysia kinesin mRNA cargo study
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Aplysia californica 
2013-04-26 | E-GEOD-30389 | biostudies-arrayexpress
TranscriptomicsSpecific kinesin expression profiles associated with taxane resistance in breast cancer
Purpose: Breast cancer is a genetically heterogenous disease with subtypes differing in prognosis and chemosensitivity. The basal-like breast cancer (BLBC) molecular subtype is associated with poorer outcomes, but is more responsive to taxane-based chemotherapy. We evaluated the role of kinesins, mo...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-22796 | biostudies-arrayexpress
ProteomicsMechanochemical tuning of a kinesin motor essential for malaria parasite transmission
Kinesins are a superfamily of molecular motors that undertake ATP-dependent microtubule-based movement or regulate microtubule dynamics. Plasmodium species, which cause malaria and kill hundreds of thousands annually, encode ~9 kinesins in their genomes. Of these, two – kinesin-8B and kinesin-8X - a...
ORGANISM(S): Plasmodium berghei ANKA 
2022-12-05 | PXD037474 | Pride
Cryo-em Malaria Microtubule Warwick_rtp Atpase Kinesin Motor Flagella 
TranscriptomicsChromosome 20q amplification regulates in vitro response to Kinesin-5 inhibitor
We identified gene expression signatures predicting responsiveness to a Kinesin-5 (kinesin spindle protein, KIF11) inhibitor (Kinesin-5i) in cultured colon tumor cell lines. Genes predicting resistance to Kinesin-5i were enriched for those from chromosome 20q, a region of frequent amplification in a...
ORGANISM(S): Homo sapiens 
2008-01-01 | GSE7969 | GEO
ProteomicsTbPH1/TbKifX2 depletion proteome
Kinesins are motor proteins found in all eukaryotic lineages that move along microtubules to mediate Kinesins are motor proteins found in all eukaryotic lineages that move along microtubules to mediate cellular processes such as mitosis and intracellular transport. In trypanosomatids, the kinesin su...
ORGANISM(S): Trypanosoma brucei 
2022-06-30 | PXD033717 | Pride
Kinesin Trypanosoma brucei Rnai 
TranscriptomicsKinesin-associated RNA: RNA co-immunoprecipitated with Kinesin IP vs RNA from Aplysia CNS
Whole genome transcriptional profiling is used to identify ESTs found in RNA co-immunoprecipitated from Aplysia CNS with antibodies against Aplysia Kinesin Heavy Chain (ApKHC) RNA derived from Aplysia CNS served as control in the opposite channel. Custom Aplysia EST array to probe the samples was de...
ORGANISM(S): Aplysia californica 
2013-04-26 | GSE30386 | GEO
Genomics
Characterization of Plasmodium Kinesin-8X
PRJNA523921 | ENA
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