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UnknownRacemic mefloquinium chloro-difluoro-acetate: crystal structure and Hirshfeld surface analysis.
Not available
S-EPMC6038619 | biostudies-literature
Unknown2-{[2,8-Bis(tri-fluoro-meth-yl)quinolin-4-yl](hy-droxy)meth-yl}piperidin-1-ium tri-chloro-acetate: crystal structure and Hirshfeld surface analysis.
Not available
S-EPMC6281115 | biostudies-literature
ProteomicsMolecular architecture of the antiophidic protein DM64 and its binding specificity to myotoxin II from Bothrops asper venom
DM64 is a toxin-neutralizing serum glycoprotein isolated from the South American opossum Didelphis aurita. This ophiophagous marsupial is naturally resistant to snake envenomation and has evolved such biochemical defense as a trophic adaptation. The endogenous antitoxin is a human α1B-glycoprotein h...
ORGANISM(S): Bothrops asper Didelphis aurita 
2022-01-20 | PXD028522 | Pride
Molecular modeling Snake venom Structural model Toxin Structure-function Mass-spectrometry Inhibitor Protein cross-linking 
UnknownSelf-Assembled Tetrahedral [Cr<sup>III</sup><sub>4</sub>L<sub>6</sub>]<sup>12+</sup> Cage Displaying Near-Infrared Spin-Flip Photoluminescence.
Not available
S-EPMC12305491 | biostudies-literature
ProteomicsChlorogenic acid mitigates calcium oxalate monohydrate crystal-induced epithelial-to-mesenchymal transition in renal epithelial cells via suppression of HSP60 expression and p38 signaling
Background: Epithelial-to-mesenchymal transition (EMT) is a prominent process involved in kidney fibrosis. Calcium oxalate monohydrate (COM), a crystalline composition predominantly found in renal stones, is one of the known stimuli that can trigger the EMT process. Chlorogenic acid (CGA), a phenoli...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2026-09-14 | PXD076150 | Pride
Cellular proteome  cga  emt  hsp60  kidney fibrosis  proteomics 
TranscriptomicsCell-type based analysis of microRNA profiles in the mouse brain
MicroRNAs (miRNA) are implicated in brain development and function but the underlying mechanisms have been difficult to study in part due to cellular heterogeneity in neural circuits. To systematically analyze miRNA expression in neurons, we have established a miRNA tagging and affinity purification...
ORGANISM(S): Mus musculus 
2011-06-29 | E-GEOD-30286 | biostudies-arrayexpress
TranscriptomicsApplication of array-CGH for the detection of genomic rearrangements responsible for syndromic mental retardation of unknown cause
Here we describe an interstitial pure duplication of 19p13.3 that was initially considered as a de novo alteration, in a patient with intellectual disability studied by array-CGH. The finding of the same chromosomal alteration in a first-degree cousin of this patient led us to investigate the presen...
ORGANISM(S): Homo sapiens 
2014-05-22 | E-GEOD-57899 | biostudies-arrayexpress
TranscriptomicsArray comparative hybridization (array-CGH) for detection of gene dose alterations in VACTERL association [4x180k Array v.031035]
The aim of the study was to screen for pathogenic gene dose alterations in patients and fetal cases with VACTERL association using a 180K oligonucleotide microarray. The experiment was performed by hybridization of genomic DNA from patients, labelled with Cy3 fluorophore, with a mix of DNA from heal...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-51956 | biostudies-arrayexpress
TranscriptomicsArray comparative hybridization (array-CGH) for detection of gene dose alterations in VACTERL association [4x180k Array v.025990]
The aim of the study was to screen for pathogenic gene dose alterations in patients and fetal cases with VACTERL association using a 180K oligonucleotide microarray. The experiment was performed by hybridization of genomic DNA from patients, labelled with Cy3 fluorophore, with a mix of DNA from heal...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-51957 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of REST/NRSF
ENCODE ChIP-chip study using 8 diverse human cell lines; 4 of neural origin (NB69, KELLY, SHSY-5Y, U373) and 4 of non-neural origin (HeLa, HepG2, HEK293 and K562) and anti-REST/NRSF antibody (Santa Cruz Biotech; sc-25398 aka H290) to asses REST-genome interactions across 1% of the human genome used...
ORGANISM(S): Homo sapiens 
2009-03-31 | E-TABM-660 | biostudies-arrayexpress
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