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UnknownEffect of Phentermine on Hepatic Steatosis in Bariatric Surgery: A Pilot Study.

Objective

Hepatic steatosis is associated with increased surgical complications in bariatric surgery patients. We aimed to evaluate the effect of phentermine in reducing hepatic steatosis, adipose tissue, and surgical complications in patients undergoing bariatric surgery.

Methods

Thi...
S-EPMC9275005 | biostudies-literature
UnknownDifferential effects of high dose omega-3 fatty acids on metabolism and inflammation in patients with obesity: eicosapentaenoic and docosahexaenoic acid supplementation.

Background

Obesity is complicated by low-grade chronic inflammation characterised by increases in inflammatory proteins and cells in peripheral blood. It has been known that omega-3 fatty acids (FA) like eicosapentaenoic (EPA) and docosahexaenoic (DHA) could modulate the inflammatory process...
S-EPMC10196397 | biostudies-literature
UnknownIn-hospital mortality from severe COVID-19 in a tertiary care center in Mexico City; causes of death, risk factors and the impact of hospital saturation.

Background

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has remained in Latin America, Mexico has become the third country with the highest death rate worldwide. Data regarding in-hospital mortality and its risk factors, as well as the impact of hospital overc...
S-EPMC7857625 | biostudies-literature
UnknownMicroRNA Expression in Cutaneous Lupus: A New Window to Understand Its Pathogenesis.

Background

The role of miRNAs in the pathogenesis of cutaneous lupus has not been studied.

Objective

It was to assess the levels of a selected panel of circulating miRNAs that could be involved in the regulation of the immune response, inflammation, and fibrosis in cutaneous lupus.
S-EPMC7012207 | biostudies-literature
UnknownLipoprotein (a) levels and clinical decision-making: data from a Mexican cohort at a tertiary medical institution.

Background and objective

Approximately 20% of the global population has a Lp(a) concentrations above 50 mg/dL (> 125nmol/L), yet many remain unaware of the associated cardiovascular risks. In Mexico, routine measurement of Lp(a) is uncommon. This study aimed to investigate the frequency of L...
S-EPMC12107857 | biostudies-literature
UnknownSera from women with different metabolic and menopause states differentially regulate cell viability and Akt activation in a breast cancer in-vitro model.
Obesity is associated with an increased incidence and aggressiveness of breast cancer and is estimated to increment the development of this tumor by 50 to 86%. These associations are driven, in part, by changes in the serum molecules. Epidemiological studies have reported that Metformin reduces the ...
S-EPMC9004774 | biostudies-literature
UnknownAssociation of Gut Microbiota with Atherogenic Dyslipidemia, and Its Impact on Serum Lipid Levels after Bariatric Surgery.
Gut microbiota has been suggested to modulate circulating lipids. However, the relationship between the gut microbiota and atherogenic dyslipidemia (AD), defined as the presence of both low HDL-C and hypertriglyceridemia, is not fully understood. Moreover, because obesity is among the main causes of...
S-EPMC9460232 | biostudies-literature
UnknownImpaired Cardiorespiratory Fitness in Type 1 Diabetes Is Associated With Metabolic Inflexibility and Specific Factors According to Sex.

Background

People with long-term type 1 diabetes have reduced cardiorespiratory fitness (CRF). We aimed to assess the influence of body composition, energy substrate use, and blood glucose control on cardiopulmonary exercise test performance in subjects with uncomplicated, long-term type 1 d...
S-EPMC12703045 | biostudies-literature
UnknownClinical characterization of data-driven diabetes subgroups in Mexicans using a reproducible machine learning approach.

Introduction

Previous reports in European populations demonstrated the existence of five data-driven adult-onset diabetes subgroups. Here, we use self-normalizing neural networks (SNNN) to improve reproducibility of these data-driven diabetes subgroups in Mexican cohorts to extend its applic...
S-EPMC7380860 | biostudies-literature
UnknownDifferentiating proven progressive disseminated histoplasmosis from other diagnoses in hospitalized persons with HIV and suspected progressive disseminated histoplasmosis: Findings from a clinical and demographic study in Mexico.

Background

Progressive disseminated histoplasmosis (PDH) is a leading cause of morbidity and mortality among persons with HIV (PWH) in the Americas. Clinical presentation often overlaps with other opportunistic infections -especially tuberculosis (TB)- and sensitive diagnostics are frequentl...
S-EPMC12453177 | biostudies-literature
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