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ProteomicsGWI Mouse model SIDL - Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of gulf war illness
Long term consequences of combined pyridostigmine bromide and permethrin exposure in C57BL6/J mice using a well characterized mouse model of exposure to these Gulf War agents. Expanding on earlier work, we used orthogonal proteomic approaches to identify pathways that are chronically impacted in the...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-01 | PXD005198 | Pride
Sidl Gwi Mouse model Gulf war illness 
ProteomicsGulf War Illness mouse model chronic iTRAQ
Long term consequences of combined pyridostigmine bromide and permethrin exposure in C57BL6/J mice using a well characterized mouse model of exposure to these Gulf War agents. Expanding on earlier work, we used orthogonal proteomic approaches to identify pathways that are chronically impacted in the...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-01 | PXD005185 | Pride
Mouse model Itraq Chronic Gulf war illness Quantitative proteomics 
ProteomicsRasGRP1 is a Causal Factor in the Development of L-DOPA-induced dyskinesia in Parkinson Disease
The therapeutic benefits of L–3,4–dihydroxyphenylalanine (L-DOPA) in Parkinson’s disease (PD) patients severely diminishes with the onset of L-DOPA-induced dyskinesia (LID), a debilitating motor side effect. LID is mainly due to altered dopaminergic signaling in the striatum, a brain region that con...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-22 | PXD017434 | Pride
Dyskinesia Parkinson disease Rasgrp1 
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