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GenomicsPRMT1 and CSNK1a1 control epidermal progenitor maintenance (PRMT1/CSNK1a1 transcriptome profiling data sets)
PRMT1 and CSNK1a1 control epidermal progenitor maintenance (PRMT1/CSNK1a1 transcriptome profiling data sets)
PRJNA432779 | ENA
GenomicsDissecting the stem cell compartment in Csnk1a1 haploinsufficiency
Dissecting the stem cell compartment in Csnk1a1 haploinsufficiency
PRJNA694424 | ENA
GenomicsPRMT1 and CSNK1a1 control epidermal progenitor maintanence (PRMT1 ChIP-seq data set)
PRMT1 and CSNK1a1 control epidermal progenitor maintanence (PRMT1 ChIP-seq data set)
PRJNA432778 | ENA
TranscriptomicsPRMT1 and CSNK1a1 control epidermal progenitor maintenance (PRMT1/CSNK1a1 transcriptome profiling data sets)
Here we determine the target gene sets controlled by PRMT1 or CSNK1a1 in maintaining the undifferentiated state of primary human keratinocytes.
ORGANISM(S): Homo sapiens 
2018-02-02 | GSE110049 | GEO
TranscriptomicsTargeting Csnk1a1 induces selective p53-dependant killing of leukemia stem cells
We found found that casein kinase 1 alpha (Csnk1a1), a serine threonine kinase and negative regulator of beta catenin, is essential for leukemia cells in vivo. We examined the effect of Csnk1a1 knowckdown by gene expression profiling in primary leukemia cells.
ORGANISM(S): Mus musculus 
2014-02-23 | E-GEOD-52928 | biostudies-arrayexpress
UnknownCsnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.
Not available
S-EPMC3978274 | biostudies-literature
TranscriptomicsAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
To characterize the role of CK1 (encoded by Csnk1a1) in skin physiology, we crossed mice with floxed Csnk1a1 with mice expressing K14CreERT2 to generate mice in which tamoxifen induces the deletion of Csnk1a1 exclusively in keratinocytes (SKO). In addition, we established K14CreERT2 CK1/p53 double-k...
ORGANISM(S): Mus musculus 
2017-08-25 | E-MTAB-5442 | biostudies-arrayexpress
TranscriptomicsDissecting the stem cell compartment in Csnk1a1 haploinsufficiency
We sorted hematopoietic progenitors from mouse bone marrow previously transplanted with either Csnk1a1 fl/+ or Mx1Cre+ bone marrow and performed scRNAseq. We identified cell populations in a continuum of differentiation from quiescent stem cell to cycling lineage-marker expressing progenitor. Our an...
ORGANISM(S): Mus musculus 
2022-02-27 | GSE165395 | GEO
UnknownCSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling.
Not available
S-EPMC10813568 | biostudies-literature
UnknownCSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q).
Not available
S-EPMC4744770 | biostudies-literature
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