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ProteomicsCSR-1A post-translational modification
CSR-1 is an essential Argonaute protein that binds to a subclass of 22G-RNAs targeting most germline-expressed genes. Here we show that the two isoforms of CSR-1 have distinct expression patterns; CSR-1B is ubiquitously expressed throughout the germline and during all stages of development while CSR...
ORGANISM(S): Caenorhabditis elegans 
2021-06-17 | PXD021227 | Pride
C. elegans Dimethylation Csr-1a 
GenomicsArgonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
Argonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
PRJNA1090893 | ENA
GenomicsArgonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
Argonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
PRJNA1090892 | ENA
TranscriptomicsArgonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
Paternal stress can be encoded into altered epigenetic information to influence their offspring. How environment-induced perturbation in sperm epigenome is reprogrammed to protect offspring is less well understood. In the nematode Caenorhabditis elegans, parental Argonaute and small RNA pathway defe...
ORGANISM(S): Caenorhabditis elegans 
2025-02-07 | GSE262244 | GEO
GenomicsArgonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring
Paternal stress can be encoded into altered epigenetic information to influence their offspring. How environment-induced perturbation in sperm epigenome is reprogrammed to protect offspring is less well understood. In the nematode Caenorhabditis elegans, parental Argonaute and small RNA pathway defe...
ORGANISM(S): Caenorhabditis elegans 
2025-02-07 | GSE262243 | GEO
UnknownArgonaute CSR-1A promotes H3K9me3 maintenance to protect somatic development in offspring.
Not available
S-EPMC11878544 | biostudies-literature
TranscriptomicsTwo isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility through distinct small RNA classes
The C. elegans genome encodes nineteen functional Argonaute proteins that utilize 22G-RNAs, 26G-RNAs, miRNAs, or piRNAs to regulate their target transcripts. Only one of these proteins is essential under normal laboratory conditions: CSR-1. While CSR-1 has been studied in various developmental and f...
ORGANISM(S): Caenorhabditis elegans 
2020-07-19 | GSE154678 | GEO
TranscriptomicsArginine methylation promotes siRNA-binding specificity for a spermatogenesis-specific isoform of the Argonaute protein CSR-1
CSR-1 is an essential Argonaute protein that binds to a subclass of 22G-RNAs targeting most germline-expressed genes. Here we show that the two isoforms of CSR-1 have distinct expression patterns; CSR-1B is ubiquitously expressed throughout the germline and during all stages of development while CSR...
ORGANISM(S): Caenorhabditis elegans 
2021-06-04 | GSE151828 | GEO
UnknownTwo isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility.
Not available
S-EPMC8421154 | biostudies-literature
UnknownArginine methylation promotes siRNA-binding specificity for a spermatogenesis-specific isoform of the Argonaute protein CSR-1.
Not available
S-EPMC8270938 | biostudies-literature
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