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Deregulation of translational control is frequently implicated in the establishment and maintenance of the cancer phenotype. Anti-cancer drugs targeting protein synthesis are confronted by the problem that genes can exploit alternative translational mechanisms. To better understand the molecular mec...
ORGANISM(S): Homo sapiens 
Sequencing of total RNA and polysomal RNA of two cell lines, MCF7 (tumoral) and MCF10A (non-tumoral) Polysomal and total RNA was prepared from biological triplicates from the two cell lines. For each biological triplicate sub-confluent cell monolyers were lysed to produce cytoplasmic extracts. Half...
ORGANISM(S): Homo sapiens 
Proteoglycans are a small but diverse family of proteins that play a wide variety of roles at the cell surface and extracellular matrix. In addition to their glycosaminoglycan (GAG) chains, they are also N- and O-glycosylated. All of these types of glycosylation are crucial to their function, but pr...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2025-05-06 | PXD041935 | Pride
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