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MetabolomicsDeciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis
The incidence of sub-fertility is higher in crossbred bulls compared to zebu bulls. In the present study, we analysed the metabolomic profile of seminal plasma from crossbred and zebu bulls and uncovered differentially expressed metabolites between these two breeds. Using a high-throughput LC-MS/MS-...
2021-12-22 | MTBLS1642 | MetaboLights
MetabolomicsMulti-omics insights into the effects of Citrus reticulata-derived Bacillus cereus C3X-5 on the fermentation quality of cigar tobacco leaves
This study investigates the potential of Bacillus cereus C3X-5, a strain isolated from Citri Reticulatae Pericarpium (CRP), as a bio-enhancer for improving cigar tobacco leaves (CTL) fermentation quality. By integrating physicochemical analysis, metagenomics, and untargeted metabolomics, we systemat...
2026-07-24 | MTBLS15119 | MetaboLights
ProteomicsPlasmodium falciparum PM X LC-MSMS
Plasmepsin X (PM X) is an aspartate protease expressed in the malaria parasie Plasmodium falciparum. Following synthesis PM X undergoes proteolytic processing. This project aims to understand the significance of PM X processing. To identify the cleavage sites, the processed PM X bands were excised f...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-10-14 | PXD035172 | Pride
Lc-msms Malaria Plasmepsin x Plasmodium 
TranscriptomicsTranscription profiling of heart left ventricles from 15 week old inbred COP, DA, and F1(COP x DA) offspring with respect to aerobic running capacity (low, high, and intermediate performers respectively)
We used high density oligonucleotide arrays to measure the relative expression levels of ~27,000 probe sets in the left ventricles of inbred rat strains; DA (high performing), Copenhagen (COP, low performing), as well as F1(COPxDA) rats bred from these tw
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1795 | biostudies-arrayexpress
GenomicsXist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing
Xist orchestrates X chromosome inactivation, a process that entails chromosome-wide silencing and remodeling of the 3-dimensional structure of the X chromosome. Yet, it remains unclear whether these changes in nuclear structure are mediated by Xist and whether they are required for silencing. Here w...
ORGANISM(S): Mus musculus 
2016-07-24 | E-GEOD-80510 | biostudies-arrayexpress
GenomicsAnalysis of the recruitment of JARID2 via Xist RNA during XCI by ChIP-seq
JARID2 ChIP-seq profile mediated by Xist was investigated using two separate approaches: In the first approach, we use the TX1072 female embryonic stem cell (ESC) line; this is a genetically polymorphic ESC line derived from a mouse with one X-chromosome (X-chr) from the Mus musculus castaneus (Cast...
ORGANISM(S): Mus musculus 
2014-01-23 | E-GEOD-52073 | biostudies-arrayexpress
ProteomicsA mouse model of Fragile X Syndrome analyzed by quantitative proteomics: a comparison of methods
We have compared the performance of seven different strategies in the analysis of a mouse model of Fragile X Syndrome, involving the knockout of the fmr1 gene that is the leading cause of autism spectrum disorder. Focusing on the cerebellum, we show that Data-Independent Acquisition (DIA) and the TM...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-21 | PXD039885 | Pride
Quantitative proteomics Boxcar Complementary ion quantification Dia Method comparison Label-free Tmt labeling Mouse brain proteomics Fragile x syndrome 
ProteomicsThe role of early chromatin changes in X chromosome inactivation
During development, transcriptional and chromatin modification changes co-occur but the order and causality of events often remain unclear. We explore the interrelationship of these processes using the paradigm of X-chromosome inactivation (XCI). We initiate XCI in female, mouse embryonic stem cells...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-17 | PXD011344 | Pride
X chromosome inactivation  mouse embryonic stem cells  epigenomics  transcriptomics  histone deacetylation  polycomb  histone acetylation 
ProteomicsSWATH-MS analysis of x-ray radiated mouse serum
After a week of acclimatization, 8-week-old mice were randomly divided into 4 groups consisting of more than 8 mice per group, and subjected to varying total body irradiation (TBI) doses of 0, 0.5, 1 or 3 Gy of X-rays (150 kVp, 20 mA, 0.5-mm aluminum and 0.3-mm copper filters) at a dose rate of 1.0 ...
ORGANISM(S): Mus Musculus (mouse) 
2022-05-12 | PXD025950 | JPOST Repository
ProteomicsProteomics analysis of the membrane vesicles in Pseudomonas aeruginosa under X-ray irradiation
Pseudomonas aeruginosa, X-ray irradiation, inner membrane blebbing, membrane vesicles Almost all bacteria produce membrane vesicles (MVs) that have been found to be generally composed of lipopolysaccharides (LPSs), phospholipids (PLs), outer membrane proteins, periplasmic proteins and peptidoglycan ...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-08-25 | PXD037062 | Pride
X-ray irradiation Membrane vesicles Proteomics analysis Pseudomonas aeruginosa 
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