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RNA-Seq shows the effect of EGFR-TKIs Dacomitinib on HaCaT cells
Dacomitinib treated HaCaT for 48 hours, Dacomitinib significantly increased Retinol metabolism pathway in HaCaT
ORGANISM(S): Homo sapiens 
2025-09-01 | GSE278965 | GEO
Numerous reagents have been developed to enable chemical proteomic analysis of small molecule-protein interactomes. However, the performance of these reagents has not been systematically evaluated and compared. Herein, we report our efforts to conduct a parallel assessment of two widely-used chemica...
ORGANISM(S): Homo sapiens (Human) 
2019-08-21 | PXD014066 | Pride
Single-cell analysis reveals dynamic changes of A549 cells in monolayer, A549 xenografts in nude mice, and xenografts after exposure to dacomitinib
The in vitro A549 cells, and A549 xenografts in nude mouse were two classic and commonly used models for anti-cancer drug discovery. Here dynamic changes of the A549 models, and also A549 xenografts after exposure to dacomitinib were revealed by single-cell transcriptome analysis.
ORGANISM(S): Homo sapiens Mus musculus 
2023-12-01 | GSE220435 | GEO
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