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GenomicsDNA Cytosine Hydroxymethylation Levels Are Distinct Among Peripheral Blood Leukocytes
Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease related stress. We considered the hypothesis that the TET enzyme catalyzed hydroxymethylation of 5mC to 5hmC might vary among peripheral blood leukocytes and reflect t...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-70519 | biostudies-arrayexpress
GenomicsSubsets of visceral adipose tissue nuclei with discrete levels of 5-hydroxymethylcytosine
We explored the hypothesis that adipose tissue contains epigenetically distinct subpopulations of adipocytes that are differentially potentiated to record cellular memories of their environment. Adipocytes are large, fragile, and technically difficult to efficiently isolate and fractionate. We devel...
ORGANISM(S): Sus scrofa 
2016-07-20 | E-GEOD-73684 | biostudies-arrayexpress
GenomicsThe alteration of 5-hydroxymethylcytosine modification contributes to ischemic brain injury [5hmC-seq]
Epigenetic modifications, such as cytosine methylation and histone modification, have been shown involved in the pathology of ischemic brain injury. Recent works have implicated 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC) through the oxidation by Ten-Eleven Translo...
ORGANISM(S): Mus musculus 
2015-09-08 | E-GEOD-67188 | biostudies-arrayexpress
ProteomicsTotal proteome analysis of WT vs TRAP1 KO in HCT-116 and HEK-293T cells grown on different carbon sources.
The molecular chaperone TRAP1, the mitochondrial isoform of cytosolic HSP90, remains poorly understood with respect to its pivotal role in the regulation of mitochondrial metabolism. To characterize the impact of TRAP1 in maintaining the cellular proteome under different energy sources we carried ou...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015828 | Pride
Oxidative phosphorylation Trap1 Mitochondrion Hsp90 Molecular chaperone 
UnknownMultiomics analysis reveals flavonoid accumulation and biosynthesis across different cultivation years and localities of <i>Gongronemopsis tenacissima</i> (Dai-Bai-Jie).
Not available
S-EPMC12716135 | biostudies-literature
UnknownPolicies and Problems of Modernizing Ethnomedicine in China: A Focus on the Yi and Dai Traditional Medicines of Yunnan Province.
Not available
S-EPMC7443223 | biostudies-literature
TranscriptomicsTranscriptomic analysis of grape (Vitis vinifera L.) leaves exposed to ultraviolet C radiation
Solar ultraviolet C（UV-C）radiation reaching the Earth’s surface is little due to the filtering effects of the stratospheric ozone layer. At present, artificial UV-C irradiation is utilized for different biological processes. Grape is a major fruit crop around the world. Research has shown that UV-C ...
ORGANISM(S): Vitis vinifera 
2014-11-15 | E-GEOD-62315 | biostudies-arrayexpress
UnknownSurface enrichment and diffusion enabling gradient-doping and coating of Ni-rich cathode toward Li-ion batteries.
Not available
S-EPMC8316340 | biostudies-literature
UnknownSurface modification using heptafluorobutyric acid to produce highly stable Li metal anodes.
Not available
S-EPMC10199051 | biostudies-literature
UnknownAssociation between C-reactive protein and atrial fibrillation recurrence after catheter ablation: a meta-analysis.
Not available
S-EPMC6649439 | biostudies-literature
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