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In temperate and sub-tropical regions of Latin America, complicated malaria manifested as hepatic dysfunction or renal dysfunction is seen in all age groups. There has been a concerted focus on understanding the patho-physiological and molecular basis of complicated malaria in children, much less is...
ORGANISM(S): Plasmodium falciparum 
Plasmodium vivax is the most geographically widespread human malaria parasite causing approximately 130-435 million infections annually. It is an economic burden in many parts of the world and poses a public health challenge along with the other Plasmodium sp. The biology of this parasite is very li...
ORGANISM(S): Plasmodium vivax 
Genomic variation is an inherent phenomena observed among members of same species belonging to different geographical locations. In case of P. falciparum, an apicomplexan protozoan parasite, its 22.8 MB nuclear genome is known to display vast genetic diversity in the subtelomeric compartments havin...
ORGANISM(S): Plasmodium falciparum 
Mechanisms regulating gene expression in malaria parasites are not well understood. Little is known about how this parasite regulates its gene expression during transition from one developmental stage to another and in response to various environmental conditions. Parasites in a diseased host face e...
ORGANISM(S): Plasmodium falciparum 
Russell’s viper (Daboia russelii) (RV), a category I medically important snake as well as a member of the “Big Four”, is responsible for a heavy toll of snake bite mortality and morbidity in Indian sub-continent. Epidemiological studies suggest highest incidence of RV envenomation in eastern India (...
ORGANISM(S): Daboia russelii 
2018-07-16 | PXD008607 | Pride
A Tale of Two Parasites: A Glimpse into the RNA Methylome of Patient-derived P. falciparum and P. vivax isolates
Nanopore methylome sequencing of Plasmodium falciparum clinical isolates to capture the single-base, genome-wide 5mC and 5hmC modifications in the CG context.
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