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ERβ1 is the predominant isoform mediating transcriptional activity in granulosa cells; however, ERβ1-specific target genes remain largely unknown. Here, we performed transcriptomic analysis of primary human granulosa cells with specific knockdown of ERβ1 and stimulation with estradiol (E2), an ERβ a...
ORGANISM(S): Homo sapiens 
Transcription profiles of three field collections of Anopheles gambiae M molecular form (i.e. Anopheles coluzzii) from West Africa were compared to investigate their phenotypic differences in insecticide resistance. The susceptibility status for the individual samples was unknown but known for their...
ORGANISM(S): Anopheles gambiae 
Transcription profiles of a field collection of Anopheles gambiae M molecular form (i.e. Anopheles coluzzii) from a population from Cote d'Ivoire (West Africa) were compared to two laboratory strains and to a wild caught field strain (all carbamate insecticide susceptible) to investigate their diffe...
ORGANISM(S): Anopheles gambiae 
Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERalpha binding regions. Onl...
ORGANISM(S): Homo sapiens 

Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory phenotype and metabolic reprogramming. Here, by using dynamic transcriptome and metabolome profiling in human fibroblasts with different subtypes ...

2024-01-09 | MTBLS7118 | MetaboLights
(i) RNA-seq of M. tuberculosis H37Rv cultures grown in the presence of BVL3572S for 6 h compared to untreated controls. (ii) Genome-wide M. tuberculosis H37Rv CRISPRi libraries were grown in the presence of ATc for 5 days prior to drug exposure. Cultures were treated with sub-MIC BVL3572S concentra...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
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