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Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
ProteomicsSpatial proteomics identifies a novel CRTC-dependent viral sensing pathway that stimulates production of Interleukin-11
Appropriate cellular recognition of viruses is essential for the generation of effective innate and adaptive antiviral immunity. Viral sensors and their signalling components thus provide a crucial first line of host defence. Many exhibit subcellular relocalisation upon activation, triggering expres...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD051850 | Pride
Interleukin-11 Proteomics  systems virology  virus signalling  sendai virus  crtc 
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
GenomicsImmune and Metabolic Features of Brain Metastases Melanoma (Cancer Discovery) Data Access Committee
Data Access Committee EGAC00001001216
EGAC00001001216 | EGA
Genomicsena-DATASET-RTL-10-04-2014-14:57:02:227-16 - samples
Fernandez-Cuesta et al, 2014, Nature Communication, Whole exome sequencing data set
EGAD00001000820 | EGA
Genomicsena-DATASET-RTL-03-04-2014-12:58:19:275-109 - samples
Fernandez-Cuesta et al., 2014, Nature Communication, Whole genome sequencing was performed using a read length of 2x100 bp for all samples. On average, 110 Gb of sequence were produced per sample, aiming a mean coverage of 30x for both tumour and matched normal.
EGAD00001000813 | EGA
GenomicsCA_SNP_6.0 - samples
SNP 6.0 arrays of carcinoid samples
EGAD00010000546 | EGA
Genomicsena-DATASET-RTL-26-03-2014-08:44:34:042-926 - samples
Fernandez-Cuesta et al, 2014, Nature Communication, RNA Sequencing data set
EGAD00001000795 | EGA
GenomicsFrequent mutations in chromatin-remodelling genes in pulmonary carcinoids
Pulmonary carcinoids are rare neuroendocrine tumours of the lung. The molecular alterations underlying the pathogenesis of these tumours have not been systematically studied so far. Here we perform gene copy number analysis (n¼54), genome/exome (n¼44) and transcriptome (n¼69) sequencing of pulmonary...
EGAS00001000650 | EGA
UnknownMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
Not available
S-EPMC6497554 | biostudies-literature
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