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ProteomicsGu-Ben-Fang-Xiao decoction ameliorates airway remodeling by regulating the PI3K/AKT signaling pathway mediated by RTN4 in a chronic remission asthma murine model
Airway remodeling is a main pathological feature of asthma. The current therapy for asthma is mainly targeted for reducing inflammation, not particularly for airway remodeling. Herein, developing alternative and more effective therapy to attenuate remodeling is worthy of further study. Gu-Ben-Fang-X...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020711 | Pride
Rtn4 Pi3k/akt pathway Gu-ben-fang-xiao decoction Chronic remission asthma Airway remodeling 
TranscriptomicsShort and long term cold responses in a winter barley
Gene expression changes in a winter cultivar of barley in response to short and long term cold treatments ****[PLEXdb(http://www.plexdb.org) has submitted this series at GEO on behalf of the original contributor, Ben Trevaskis. The equivalent experiment is BB94 at PLEXdb.] treatment: Non-vernali...
ORGANISM(S): Hordeum vulgare 
2011-03-08 | E-GEOD-27821 | biostudies-arrayexpress
TranscriptomicsCharacterization of the coding and noncoding transcriptome in undifferentiated and differentiating mouse embryonic stem cells
RNA (poly(A)+ fraction) has ben isolated from undifferentiated mouse embryonic stem cells and from embryonic stem cells induced to differentiate using the hanging drop model, 6 days following iinduction of differentiation. Profiling of the transcritome at these two stages of differentiation using de...
ORGANISM(S): Mus musculus 
2014-09-25 | E-GEOD-60097 | biostudies-arrayexpress
TranscriptomicsEvaluation of the robustness of classification of carcinogen-modified transcriptomic responses in HepaRG cells and the interlaboratory reproducibility of the model
Efforts to develop alternatives which can at least partially replace some of the currently used in vivo tests are ongoing. The recently ended FP6 European project carcinoGENOMICS had the goal to use the combination of toxicogenomics and in vitro cell culture models for identification of genotoxic- a...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-48990 | biostudies-arrayexpress
TranscriptomicsEarly response of gene expression in the distal intestine of Atlantic salmon (Salmo salar L.) during the development of soybean meal induced enteritis
In the present study a 44k oligonucleotide salmonid microarray, qPCR and histology were used to investigate transcriptomic responses in the distal intestine during the first week of oral exposure to soybean meal in order to gain insight into early molecular response mechanisms. Intestinal tissue sam...
ORGANISM(S): Salmo salar 
2012-12-17 | E-GEOD-37457 | biostudies-arrayexpress
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
UnknownMolecular Insights into Bacteriophage Evolution toward Its Host.
Not available
S-EPMC7599783 | biostudies-literature
UnknownFeasibility and Efficacy of Partially Replacing Post-Transplantation Cyclophosphamide with Bendamustine in Pediatric and Young Adult Patients Undergoing Haploidentical Bone Marrow Transplantation.
Not available
S-EPMC9253073 | biostudies-literature
UnknownA single birth dose of Hepatitis B vaccine induces polyfunctional CD4+ T helper cells.
Not available
S-EPMC9681035 | biostudies-literature
TranscriptomicsGenomic analysis of hESC pedigrees enables identification of de novo genetic alterations and determination of the timing and origin of mutational events
Given the association between mutational load and cancer, the observation that genetic aberrations are frequently found in human pluripotent stem cells (hPSCs) is of concern. Prior studies in hiPSCs have shown that deletions and regions of loss-of-heterozygosity (LOH) tend to arise during reprogramm...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-49452 | biostudies-arrayexpress
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