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MetabolomicsMetabolically-incorporated deuterium in myelin localized by neutron diffraction and identified by mass spectrometry
Myelin is a natural and dynamic multilamellar membrane structure that continues to be of significant biological and neurological interest, especially with respect to its biosynthesis and assembly during its normal formation and maintenance, and pathological breakdown. To explore the usefulness of ne...
2024-09-27 | MTBLS4717 | MetaboLights
UnknownClinical Analytics Prediction Engine (CAPE): Development, electronic health record integration and prospective validation of hospital mortality, 180-day mortality and 30-day readmission risk prediction models.
Not available
S-EPMC7451512 | biostudies-literature
TranscriptomicsEffects of moderate ethanol consumption during pregnancy on placental gene expression
We conducted a preliminary investigation to determine whether ethanol-induced alterations in placental gene expression may have some utility as a diagnostic indicator of maternal drinking during pregnancy as well as a prognostic indicator of risk for adverse neurobehavioral outcomes in affected offs...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-18162 | biostudies-arrayexpress
TranscriptomicsS080_BrCaRes_Schneeweiss et al.
In patients with primary breast cancer, neoadjuvant chemotherapy with doxorubicin plus pemetrexed followed by docetaxel (AP-D) is associated with a pathologic complete response (pCR) rate of 16.5%, and doxorubicin plus cyclophosphamide followed by docetaxel (AC-D) is associated with a pCR rate of 20...
ORGANISM(S): Homo sapiens 
2014-02-01 | E-TABM-1186 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [double KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68725 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [VDR KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68723 | biostudies-arrayexpress
TranscriptomicsP19 embryonic carcinoma (EC) cells induced to form cardiomyocytes in vitro
SAGE identification of differentiation responsive genes in P19 embryonic cells induced to form cardiomyocytes in vitro. P19 embryonic carcinoma (EC) cells, induced to form cardiomyocytes in vitro - undifferentiated cells, day 3+0.5 and day 3+3.0 of differentiation protocol. Keywords = EC cells, P19,...
ORGANISM(S): Mus musculus 
2002-07-18 | E-GEOD-42 | biostudies-arrayexpress
MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
TranscriptomicsGene expression based profiling of brains from mice infected with lethal Listeria monocytogenes over a 4-day period
Data presented here show that gene expression in the mouse brain changes during systemic infection relative to a steady state (uninfected control) mouse during systemic Listeria monocytogenes infection. Microarray analysis of gene expression in the brain following i.v. inoculation of 1-2 LD 50 L. ...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-10416 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to stress throughout a 15-day wine fermentation
We used genome-wide expression analyses to study the response of Saccharomyces cerevisiae to stress throughout a 15-day wine fermentation. Forty percent of the yeast genome significantly changed expression levels to mediate long-term adaptation to an environment in which ethanol is both a stressor a...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8536 | biostudies-arrayexpress
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