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MetabolomicsStrain level differences in marine microbial parasite-host metabolites and host mortality dynamics

Parasitism is a widespread source of mortality among marine microbial communities, with members of the diverse alveolate group Syndiniales being most prevalent and frequently identified in global omics studies. Despite their ubiquity, not much is known about Syndiniales parasite-host infection dy...

2026-10-05 | MTBLS11219 | MetaboLights
ProteomicsMulti-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptionalrepression during oogenesis
EHMT1 (also known as GLP) is a multifunctional protein, best known for its role as an H3K9me1 and H3K9me2 methyltransferase through its reportedly obligatory dimerization with EHMT2 (also known as G9A). Here, we investigated the role of EHMT1 in the oocyte in comparison to EHMT2 using oocyte-specifi...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-30 | PXD030265 | Pride
Epigenetics Histone modification Histone methyltransferase Glp/ehmt1 H3k9 methylation Dna methylation Oocyte 
GenomicsPPARG regulated genes in the day 14 ovine conceptus
PPARG ChIP seq analysis was conducted to determine genes bound by and potentially regulated by PPARG in the developing ovine conceptus. Determination of gene regulation by prostaglandins through PPARG helps to improve our understanding of early pregnancy events and provides a basis for strategies to...
ORGANISM(S): Ovis aries 
2014-07-03 | E-GEOD-59011 | biostudies-arrayexpress
TranscriptomicsMiRNA Expression data from Tk6 cell treated with arsenic, gamma-IR, or grown under folate-deficiency
Folate deficiency, arsenic exposure, and gamma-IR are known developmental toxicants and have carcinogenic effects. The mechanism by which IR is known, but the effect of arsenic or folate deficiency remains unclear. Their effect may be mediated by epigenetic alterations, leading to miRNA expression...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-6020 | biostudies-arrayexpress
TranscriptomicsExtracellular Vesicles Originate from the Conceptus and Uterus During Early Pregnancy in Sheep
The present studies tested the hypothesis that the elongating ovine conceptus and uterus produces EVs with the potential to mediate conceptus-maternal communication during early pregnancy. In Study One, EVs were purified from uterine luminal fluid (ULF) of day 14 cyclic sheep. The EVs were fluoresce...
ORGANISM(S): Ovis aries 
2015-12-16 | E-GEOD-76035 | biostudies-arrayexpress
ProteomicsFOXA2 controls the anti-oxidant response in FH-deficient cells independent of NRF2
Hereditary Leiomyomatosis and renal cell cancer (HLRCC) is caused by germline mutations of fumarate hydratase (FH) and subsequence accumulation of fumarate. Fumarate is known to activate the anti-oxidant response by KEAP1 succination and nuclear translocation of the transcription factor NRF2. The ac...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-20 | PXD034141 | Pride
Anti-oxidant response Nrf2 Fumarate hydratase Foxa2 
GenomicsMus musculus
Mapping Gene Expression in Excitatory Neurons During Hippocampal Late-Phase Long-term Potentiation
PRJNA316996 | ENA
UnknownMapMySmoke: feasibility of a new quit cigarette smoking mobile phone application using integrated geo-positioning technology, and motivational messaging within a primary care setting.
Not available
S-EPMC5513177 | biostudies-literature
UnknownAntidiabetogenic effects of hydroxychloroquine on insulin sensitivity and beta cell function: a randomised trial.
Not available
S-EPMC4575248 | biostudies-literature
UnknownEvaluation of Three Hydration Strategies in Detection Dogs Working in a Hot Environment.
Not available
S-EPMC5662554 | biostudies-literature
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