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ISG15 is a ubiquitin-like modifier strongly upregulated in the type I interferon response. It exerts an antiviral function in the host defense against a wide variety of viruses. Recently, we observed that ISG15 expression restricts coxsackievirusB3 (CV) infection both in vitro and in vivo. ISG15-dep...
ORGANISM(S): Mus musculus (Mouse) Coxsackievirus 
2019-12-09 | PXD013259 | Pride
The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) is a community-based study where all men and women at age 70 living in Uppsala, Sweden were invited to participate in 2001. The 1,016 participants (50% women) have been extensively phenotyped. In March 2006 a reinvesigation ...
2014-08-30 | MTBLS90 | MetaboLights
The TwinGene project, conducted between 2004 and 2008, is a population-based Swedish study of twins born between 1911 and 1958. The study participants have previously participated in a telephone interview called Screening Across the Lifespan Twin Study, conducted between 1998 and 2002. To be include...
2014-08-30 | MTBLS93 | MetaboLights
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related diseases in laboratory animals is greatly sought after. We and others ha...
ORGANISM(S): Mus musculus 
This data set includes the following summary level data file used for the exome chip analysis: exome_chip.sv.assoc.txt: results from single variant association analysis in exome chip
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
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