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ProteomicsIdentification of indisulam-mediated DCAF15 interacting proteins by TurboID and shotgun proteomics
In this project, we used proximity labeling with TurboID to identify proteins that interact with DCAF15 in the presence of indisulam in a gastric cancer AGS cell line.
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD024168 | Pride
Human Ags Turboid Dcaf15 Orbitrap fusion lumos Lc-ms/ms 
GenomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [HiC]
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [HiC]
PRJNA1008732 | ENA
GenomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_dTAG]
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_dTAG]
PRJNA1105321 | ENA
GenomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [ChIP-seq]
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [ChIP-seq]
PRJNA1008730 | ENA
GenomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_CRISPR]
CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_CRISPR]
PRJNA1008731 | ENA
UnknownDCAF15 control of cohesin dynamics sustains acute myeloid leukemia.
Not available
S-EPMC11222469 | biostudies-literature
OtherCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [HiC]
The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. However, the physiological function of DCAF15 remains unknown. Using a domain-focused genetic screening approach, we rev...
ORGANISM(S): Homo sapiens 
2024-05-22 | GSE241580 | GEO
GenomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [ChIP-seq]
The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. However, the physiological function of DCAF15 remains unknown. Using a domain-focused genetic screening approach, we rev...
ORGANISM(S): Homo sapiens 
2024-05-22 | GSE241579 | GEO
TranscriptomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_CRISPR]
The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. However, the physiological function of DCAF15 remains unknown. Using a domain-focused genetic screening approach, we rev...
ORGANISM(S): Homo sapiens 
2024-05-22 | GSE241578 | GEO
TranscriptomicsCRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_dTAG]
The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. However, the physiological function of DCAF15 remains unknown. Using a domain-focused genetic screening approach, we rev...
ORGANISM(S): Homo sapiens 
2024-05-22 | GSE266010 | GEO
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