Sort   by:  
 Page size 
MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
UnknownA curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing.
Not available
S-EPMC24009 | biostudies-literature
ProteomicsDirect mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum
Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder, leading to the presence of monoclonal antibody (i.e., M-protein) in serum, without clinical symptoms. Here we present a case study in which we detect MGUS by liquid-chromatography coupled with mass spectrometry (LC-...
ORGANISM(S): Homo sapiens (Human) 
2023-09-14 | PXD042266 | Pride
Antibody Glycoproteomics M-protein De novo 
ProteomicsFc glycosylation status of Vi vaccine-induced antibodies
Conjugate vaccine against typhoid fever has been shown to be safe and effective in field trials. The mechanism through which the vaccine protects remains elusive. Recent data have implicated antibody glycosylation, and specifically afucosylated antibodies, as an important factor in vaccine-induced e...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD037239 | Pride
Immunoglobulin Igg Glycan Vaccine Thyphoid fever 
ProteomicsFc glycosylation status of Vi vaccine-induced antibodies following polysaccharide or conjugate Salmonella Typhi vaccine in UK adults and Nepalese children
Conjugate vaccine against typhoid fever has been shown to be safe and effective in field trials. The mechanism through which the vaccine protects remains elusive. Recent data have implicated antibody glycosylation, and specifically afucosylated antibodies, as an important factor in vaccine-induced e...
ORGANISM(S): Homo sapiens (Human) 
2024-05-30 | PXD037251 | Pride
Igg Glycan Thyphoid fever Vaccine 
UnknownBinding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.
Not available
S-EPMC2806771 | biostudies-literature
ProteomicsIgA deglycosylation to identify glycosylation sites
In order to provide information on the peptide sequence of the IgA glycopeptides, a proteomics analysis was run on LC-MS/MS data of N-glycosidase F-digested IgA samples, in which the N-glycans had been released. The samples included IgA (isolated) from: 1) the saliva samples from two healthy donors,...
ORGANISM(S): Homo sapiens (Human) 
2018-11-09 | PXD011228 | Pride
Iga Secretory iga Plasma Colostrum Saliva 
UnknownHuman plasma IgG1 repertoires are simple, unique, and dynamic.
Not available
S-EPMC8691384 | biostudies-literature
UnknownMutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.
Not available
S-EPMC11041692 | biostudies-literature
UnknownPrecision evaluation of 2 CT-based radiostereometric analysis systems in a cadaver study.
Not available
S-EPMC12645134 | biostudies-literature
Sort   by:  
 Page size