Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of homozygous Commd1 null mouse embryos to elucidate the underlying mechanism leading to embryonic lethality
A gene expression study using microarray analysis was performed to elucidate the underlying mechanism leading to embryonic lethality in homozygous Commd1 null (Commd1-/-) mouse embryos. A gene expression profile of 9.5 dpc Commd1-/- embryos were generated and were compared to a gene expression profi...
ORGANISM(S): Mus musculus 
2006-09-01 | E-MEXP-832 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of baboon organs to identify host responses to Gram positive (S. pyogenes) or Gram negative (E. coli) induced sepsis
The aim of the project is to identify the host response related to Gram positive (S. pyogenes) or Gram negative (E. coli) induced sepsis in a controlled sepsis model. Therefore a well defined baboon sepsis model, established at the Ludwig Boltzmann Institute for experimental and clinical traumatolog...
ORGANISM(S): Papio hamadryas 
2010-04-27 | E-MARS-14 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of baboon organs to identify late host responses to Gram positive (S. pyogenes) or Gram negative (E. coli) induced sepsis
The aim of the project is to identify the late (24h) host response related to Gram positive (S. pyogenes) or Gram negative (E. coli) induced sepsis in a controlled sepsis model 24 hours a. Therefore a well defined baboon sepsis model, established at the Ludwig Boltzmann Institute for experimental an...
ORGANISM(S): Papio hamadryas 
2010-04-27 | E-MARS-15 | biostudies-arrayexpress
TranscriptomicsPredicting the efficacy of anthracyclines in breast cancer (BC) patients: The results of the TOP trial
PURPOSE: Validated biomarkers predictive of response/resistance to anthracyclines in breast cancer are currently lacking. The neoadjuvant TOP trial, in which patients with estrogen receptor (ER)-negative tumors were treated with anthracycline (epirubicin) monotherapy, was specifically designed to ev...
ORGANISM(S): Homo sapiens 
2010-01-26 | E-GEOD-16446 | biostudies-arrayexpress
TranscriptomicsA Modular Bioinstructive Platform For Additive-Free Control of Stem Cell Differentiation and Patterning
Recreating 3D bone formation in vitro without biochemical inducers remains a longstanding challenge in preclinical testing. We present a modular, bioinstructive platform based on polylactic acid microparticles with controlled dimpled surface features that direct mesenchymal stem cell differentiation...
ORGANISM(S): Homo sapiens 
2026-07-01 | E-MTAB-15393 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dfferentiation of human bone marrow derived hMSC with beta-glycerphosphate, ascorbicacidphosphate and dexamethasone for 21 days;evaluated time points d4, d7, d14 and d21 after induction
Differentiation of bone marrow derived hMSC with beta-glycerphosphate, ascorbicacidphosphate and dexamethasone for 21 days;evaluated time points d4, d7, d14 and d21 after induction; reference d-1 (one day before induction; preconfluent 70-80%)
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-3 | biostudies-arrayexpress
TranscriptomicsMultifaceted dysfunction of infant airway macrophages in response to Mycobacterium tuberculosis
Infants are vulnerable to disseminated forms of tuberculosis and suffer disproportionately high morbidity and mortality, but the reasons for this are unknown. We hypothesized that since alveolar macrophages (AMs) are critical in the uptake and containment of Mycobacterium tuberculosis (Mtb) in the l...
ORGANISM(S): Homo sapiens 
2020-03-12 | E-MTAB-7679 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of heptatocytes from mice given a high-copper diet
In order to study the physiological consequences of a high-copper diet on hepatic gene expression, 6 mM CuCl2 was added to the drinking water for a period of 1 month. After this period, livers of seven control mice and eight copper-treated mice were isolated and were subjected to microarray analysis...
ORGANISM(S): Mus musculus 
2007-06-01 | E-MEXP-745 | biostudies-arrayexpress
no omics definedTranscription profiling of human hepatocytes in response to copper overload at nine time points
Nine time points for microarray analysis were chosen to study early and late transcriptional responses in copper metabolism upon copper overload in HepG2 cells. Samples of copper-treated cells were hybridized using non-treated samples as a reference.
ORGANISM(S): Homo sapiens 
2007-06-01 | E-MEXP-753 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of in vitro / in vivo osteoblast comparison-Comparison of in vivo and in vitro developed human osteoblasts
Comparison of the genetic profile of hBM-MSC differentiated in vitro into osteoblasts with in vivo developed osteoblasts derived from hip bone.
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-4 | biostudies-arrayexpress
Sort   by:  
 Page size