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UnknownA Novel PiRNA Enhances CA19-9 Sensitivity for Pancreatic Cancer Identification by Liquid Biopsy.
Pancreatic cancer is one of the deadliest tumours worldwide, and its poor prognosis is due to an inability to detect the disease at the early stages, thereby creating an urgent need to develop non-invasive biomarkers. P-element-induced wimpy testis (PIWI) proteins work together with piwi-interacting...
S-EPMC9784851 | biostudies-literature
TranscriptomicsTranscription profiling of bone marrow samples from human acute myeloid leukemia patients
Gene expression profile of acute myeloid leukemia. Bone marrow (BM) samples from 43 adult patients with newly de novo diagnosed AML.All samples contained more than 80% blast cells. Total RNA was extracted using Trizol reagent (Life Technologies, Gaithersburg, MD) and purified with RNeasy Mini Kit (Q...
ORGANISM(S): Homo sapiens 
2007-08-14 | E-GEOD-1729 | biostudies-arrayexpress
UnknownARID1A-BAF coordinates ZIC2 genomic occupancy for epithelial-to-mesenchymal transition in cranial neural crest specification.
The BAF chromatin remodeler regulates lineage commitment including cranial neural crest cell (CNCC) specification. Variants in BAF subunits cause Coffin-Siris syndrome (CSS), a congenital disorder characterized by coarse craniofacial features and intellectual disability. Approximately 50% of individ...
S-EPMC11480806 | biostudies-literature
UnknownBacterial immunotherapy is highly effective in reducing recurrent upper respiratory tract infections in children: a prospective observational study.

Purpose

Whilst immunotherapy is an appealing option as it could reduce the burden of recurrent pediatric respiratory tract infections (RTI), there is limited evidence on its effectiveness and more research was requested in order to better understand this therapeutic modality.

Methods

...
S-EPMC10477114 | biostudies-literature
TranscriptomicsTranscription profiling of tomato seedlings Condine wild type vs. Divaricata a-DOX2 mutant
Gene expression of Condine wild type tomato seedling aerial parts grown on MS medium was compared with that of alpha-dioxygenase2 Divaricata (div) mutant
ORGANISM(S): Lycopersicon esculentum 
2009-09-25 | E-MEXP-2265 | biostudies-arrayexpress
UnknownImmunosuppressed patients with COVID-19 pneumonia in ICU: clinical characteristics and factors influencing outcomes.

Introduction

COVID-19 severely impacted global health, especially older adults and those with comorbidities. Immunosuppressed patients are at high risk for severe outcomes, yet studies yield conflicting mortality rates for this group. This study examines the clinical characteristics and outc...
S-EPMC12645730 | biostudies-literature
UnknownValidation of the RIM Score-COVID in the Spanish SEMI-COVID-19 Registry.
The significant impact of COVID-19 worldwide has made it necessary to develop tools to identify patients at high risk of severe disease and death. This work aims to validate the RIM Score-COVID in the SEMI-COVID-19 Registry. The RIM Score-COVID is a simple nomogram with high predictive capacity for ...
S-EPMC9862219 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis roots with or without treatment with 9-hydroxyoctadecatrienoic acid
Gene expression of roots grown on MS medium versus MS+9HOT was compared. 6-day-old seedlings grown on MS were transferred to fresh plates and grown for 3- or 5- additional days in the absence or in the presence of 9-HOT (25 um). Root fragments grown after transferring to fresh plates were excised an...
ORGANISM(S): Arabidopsis thaliana 
2009-10-02 | E-ATMX-14 | biostudies-arrayexpress
UnknownMetallomic Signatures of Lung Cancer and Chronic Obstructive Pulmonary Disease.
Lung cancer (LC) is the leading cause of cancer deaths, and chronic obstructive pulmonary disease (COPD) can increase LC risk. Metallomics may provide insights into both of these tobacco-related diseases and their shared etiology. We conducted an observational study of 191 human serum samples, inclu...
S-EPMC10532173 | biostudies-literature
UnknownArray CGH Analysis of Paired Blood and Tumor Samples from Patients with Sporadic Wilms Tumor.
Wilms tumor (WT), the most common cancer of the kidney in infants and children, has a complex etiology that is still poorly understood. Identification of genomic copy number variants (CNV) in tumor genomes provides a better understanding of cancer development which may be useful for diagnosis and th...
S-EPMC4552764 | biostudies-literature
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