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TranscriptomicsmRNA expression profiles of SK-N-AS neuroblastoma cells with induced ALK-wt, ALK-F1174L or ALK-R1275Q
Establishment of inducible SK-N-AS ALKwt, ALKF1174L and ALKR1275Q cell lines Human neuroblastoma SK-N-AS cells were electroporated with pcDNA6/TR (Invitrogen) using the NeonM-eM-( Transfection System (Life Techologies). Single cell clones were generated using blasticidin (7.5M-eM-5g/ml) and limited ...
ORGANISM(S): homo sapiens 
2015-05-04 | E-MTAB-3207 | biostudies-arrayexpress
ProteomicsMudPIT analyses of whole cell extracts from Y1 murine adrenocortical carcinoma cell line stimulated with serum or FGF2
Fibroblast growth factor 2 (FGF2) is well known as a promoter of cell proliferation, however, in some cellular contexts, it can induce cell cycle arrest or cell death. In Y1 murine adrenocortical carcinoma cell line, FGF2 induces G0/G1 transition but delays S-phase progression and permanently block ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-10-23 | MSV000081638 | MassIVE
UnknownApoptosis Induction of Agave lechuguilla Torrey Extract on Human Lung Adenocarcinoma Cells (SK-LU-1).
Not available
S-EPMC6321503 | biostudies-literature
Transcriptomics4C sequencing for the SOX11 promoter in the neuroblastoma cell lines CLB-GA, KELLY, SK-N-AS and SH-EP
4C sequencing for the SOX11 promoter in the neuroblastoma cell lines CLB-GA, KELLY, SK-N-AS and SH-EP.
ORGANISM(S): Homo sapiens 
2023-02-19 | E-MTAB-12580 | biostudies-arrayexpress
TranscriptomicsmRNA expression profiles of TAE-684 treated or shALK transfected neuroblastoma cell lines
Human wild-type ALK (SK-N-AS, NGP, IMR-32), ALKR1275Q (CLB-GA, LAN-5, UKF-NB-3), ALKF1174L (SK-N-SH, Kelly, SMS-KCNR) and ALK amplified (NB-1) neuroblastoma cell lines were treated in triplicate with 0.3M-k_M NPV-TAE-684 (Novartis/SelleckChem) or DMSO (VWR) for 6 hours, followed by RNA isolation and...
ORGANISM(S): Homo Sapiens 
2015-05-04 | E-MTAB-3205 | biostudies-arrayexpress
ProteomicsNeuronal cells from ASL patients
This study describes altered CREB-dependent activity related transcription, and disrupted synaptic composition as common pathological features in ALS. These aberrations are restored by Apamin and XE991, two K+ channel blockers targeting the SK and Kv7 channels and modulating neuronal excitability.Th...
ORGANISM(S): Homo sapiens (Human) 
2021-05-11 | PXD020316 | Pride
Asl Motoneurons Label free 
MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
UnknownConsistency and Stability of Motor Subtype Classifications in Patients With de novo Parkinson's Disease.
Not available
S-EPMC7957002 | biostudies-literature
TranscriptomicsTranscription profiling of yeast wild type, set1delta and swd3delta SK1 diploid cells in response to sporulation conditions, in order to determine the influence of histone methylation on the meiotic transcriptome
We analysed the global gene expression profile of wild-type, set1delta and swd3delta Saccharomyces cerevisiae SK1 diploid cells in response to sporulation conditions, in order to determine the influence of histone methylation on the meiotic transcriptome.
ORGANISM(S): Saccharomyces cerevisiae 
2004-05-05 | E-MEXP-41 | biostudies-arrayexpress
UnknownControlling Ca2+-activated K+ channels with models of Ca2+ buffering in Purkinje cells.
Not available
S-EPMC3411306 | biostudies-literature
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