Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse motorneurons during progression of the disease in transgenic SOD1(G93A) mice that develop motorneuron loss
To identify candidate genes that may be involved in motoneuron degeneration, we combined laser capture microdissection with microarray technology. Gene expression in motoneurons was analyzed during the progression of the disease in transgenic SOD1(G93A) mice that develop motoneuron loss. Three major...
ORGANISM(S): Mus musculus 
2005-10-30 | E-MEXP-453 | biostudies-arrayexpress
ProteomicsDeep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics
The fatal neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron disease and genetic cause of infant death, respectively. Various in vitro model systems have been established to investigate motoneuron disease mechanisms - in p...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084939 | MassIVE
ProteomicsProteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3’UTR binding
Increasing evidence suggests that in Amyotrophic Lateral Sclerosis (ALS) mutated RNA binding proteins acquire aberrant functions, leading to altered RNA metabolism with significant impact on encoded protein levels. Here, by taking advantage of a human induced Pluripotent Stem Cell (hiPSC)-based mode...
ORGANISM(S): Homo sapiens (Human) 
2020-10-27 | PXD019596 | Pride
Motoneurons Fus protein Vcp  asap1  3’utr  
Genomicssingle-cell RNA-seq of embryonic Drosophila motoneurons
single-cell RNA-seq of embryonic Drosophila motoneurons
PRJNA650412 | ENA
GenomicsDLK-gated responses in motoneurons following sciatic nerve crush
DLK-gated responses in motoneurons following sciatic nerve crush
PRJNA883417 | ENA
ProteomicsLoss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin
Neurons critically rely on the functions of RNA-binding proteins to maintain their polarity and resistance to neurotoxic stresses. HnRNP R has a diverse range of post-transcriptional regulatory functions and is important for neuronal development by regulating axon growth. Hnrnpr pre-mRNA undergoes a...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-01 | PXD026407 | Pride
Hnrnp r Yb1 Dna damage Motoneuron 
GenomicsMolecular Logic of Synaptic Diversity Between Drosophila Tonic and Phasic Motoneurons
Molecular Logic of Synaptic Diversity Between Drosophila Tonic and Phasic Motoneurons
PRJNA924323 | ENA
TranscriptomicsTranscription profiling of mouse lateral, medial and intermediolateral column motoneurons following spinal cord transection
To determine spinal cord injury (SCI) induced changes in gene expression, laser capture microscopy (LCM) and Affymetrix microarrays were used to profiles three distinct populations of motor neurons (MNs) in five sets of littermates. In each set, one littermate received a lamenectomy (sham operated),...
ORGANISM(S): Mus musculus 
2009-09-25 | E-GEOD-18179 | biostudies-arrayexpress
ProteomicsLoss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to Chromatin
Neurons critically rely on the functions of RNA-binding proteins to maintain their polarity and resistance to neurotoxic stresses. HnRNP R has a diverse range of post-transcriptional regulatory functions and is important for neuronal development by regulating axon growth. Hnrnpr pre-mRNA undergoes a...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-01 | PXD022467 | Pride
Proteomics Hnrnpr Ip Ftld Als Motoneurons Dna damage response 
GenomicsExpression Profile Analysis of Rat Motoneurons During Myelination
Expression Profile Analysis of Rat Motoneurons During Myelination
PRJNA552365 | ENA
Sort   by:  
 Page size