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ProteomicsLoss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin
Neurons critically rely on the functions of RNA-binding proteins to maintain their polarity and resistance to neurotoxic stresses. HnRNP R has a diverse range of post-transcriptional regulatory functions and is important for neuronal development by regulating axon growth. Hnrnpr pre-mRNA undergoes a...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-01 | PXD026407 | Pride
Hnrnp r Yb1 Dna damage Motoneuron 
GenomicsGenome-wide characterization of cis-acting DNA targets of OsNF-YB1 in rice
OsNF-YB1 is a transcription factor that plays important roles during rice grain filling. OsNF-YB1 is specifically expressed in aleurone layer of developing endosperm and OsNF-YB1 RNAi lines showed retardation in grain filling and produced small grains with chalky endosperm as well as the altered sta...
ORGANISM(S): Oryza sativa 
2016-12-16 | GSE72186 | GEO
GenomicsGenome-wide maps in breast cancer MDA-MB-231 cells with or without siRNA interference of YB1.
Genome-wide maps in breast cancer MDA-MB-231 cells with or without siRNA interference of YB1.
PRJNA1067513 | ENA
UnknownYB1 modulates the DNA damage response in medulloblastoma.
Not available
S-EPMC10199100 | biostudies-literature
TranscriptomicsGenome-wide maps in breast cancer MDA-MB-231 cells with or without siRNA interference of YB1.
Analysis of MDA-MB-231 cells following YB1 siRNA interference or not. YB1 regulates various RNA metabolic process in MDA-MB-231 cells.Results provide insight into the role of YB1-involved mechanisms underlying YB1-mediated effects on breast cancer stemness.
ORGANISM(S): Homo sapiens 
2026-06-30 | GSE253831 | GEO
TranscriptomicsThe effects of YB1 knockdown on global gene expression in tumour cell lines.
Y-box binding factor 1 (YB1) has been associated with prognosis in many tumor types. Reduction of YB-1 inhibits tumor cell growth in vitro and in vivo Total RNA was isolated from A549, MCF7 and HCT116 tumor cell lines following 48hr treatment with 5nM Yb1 siRNA
ORGANISM(S): Homo sapiens 
2011-11-30 | E-GEOD-28433 | biostudies-arrayexpress
UnknownFBXW11 inhibits tumorigenesis by ubiquitinating YB1 in hepatocarcinoma.
Not available
S-EPMC12433413 | biostudies-literature
UnknownYB1 dephosphorylation attenuates atherosclerosis by promoting CCL2 mRNA decay.
Not available
S-EPMC9386362 | biostudies-literature
TranscriptomicsAtNF-YB1 and CBF4 Overexpression Study in Arabidopsis
The baseline transcriptional profiles of Arabidopsis seedling shoots overexpressing CBF4 or AtNF-YB1 were compared with wild-type controls. Keywords: overexpression_study
ORGANISM(S): Arabidopsis thaliana 
2007-09-26 | GSE8455 | GEO
UnknownYB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.
Not available
S-EPMC8904596 | biostudies-literature
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