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ProteomicsDeep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics
The fatal neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron disease and genetic cause of infant death, respectively. Various in vitro model systems have been established to investigate motoneuron disease mechanisms - in p...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084939 | MassIVE
TranscriptomicsIdentification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors
This SuperSeries is composed of the following subset Series: GSE9603: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on NIA 15k microarray GSE9619: Identification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on ...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-9620 | biostudies-arrayexpress
ProteomicsDeep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics
The fatal neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron disease and genetic cause of infant death, respectively. Various in vitro model systems have been established to investigate motoneuron disease mechanisms - in p...
ORGANISM(S): Mus musculus (Mouse) 
2014-09-09 | PXD000666 | Pride
Neuron Amyotrophic lateral sclerosis Als Neurodegeneration Quantitative proteomics Motoneuron 
OtherDeep proteomic evaluation of primary and cell line motoneuron disease models delineates major differences in neuronal characteristics
Data from ProteomeXchange, PXD ID: PXD000666. File: 20120710_EXQ4_DaHo_SA_labelfree_7D_MN1_3_12_2.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 5 . From the Abstract: {{i}} The fatal neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the ...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32320003403 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscription profiling of mouse motorneurons during progression of the disease in transgenic SOD1(G93A) mice that develop motorneuron loss
To identify candidate genes that may be involved in motoneuron degeneration, we combined laser capture microdissection with microarray technology. Gene expression in motoneurons was analyzed during the progression of the disease in transgenic SOD1(G93A) mice that develop motoneuron loss. Three major...
ORGANISM(S): Mus musculus 
2005-10-30 | E-MEXP-453 | biostudies-arrayexpress
GenomicsR-Roscovitine improves motoneuron function in mouse models for Spinal Muscular Atrophy.
R-Roscovitine improves motoneuron function in mouse models for Spinal Muscular Atrophy.
PRJNA448923 | ENA
TranscriptomicsIdentification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on NIA 15k microarray
Branchiomotor neurons are an important class of cranial motor neurons that innervate the branchial-arch-derived muscles of the face, jaw and neck. They arise in the ventralmost progenitor domain of the rhombencephalon characterized by expression of the homeodomain transcription factors Nkx2.2 and Ph...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-9603 | biostudies-arrayexpress
TranscriptomicsIdentification of Phox2b-regulated genes by expression profiling of cranial motoneuron precursors on NeuroDev microarray
Branchiomotor neurons are an important class of cranial motor neurons that innervate the branchial-arch-derived muscles of the face, jaw and neck. They arise in the ventralmost progenitor domain of the rhombencephalon characterized by expression of the homeodomain transcription factors Nkx2.2 and Ph...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-9619 | biostudies-arrayexpress
ProteomicshnRNPR interactome in axons and soma of murine motoneurons
We determined the protein interaction partners of hnRNP R in murine motoneuron axons and soma by immunoprecipitation-MS. The neurons were grown in microchambers and axons and soma could be harvested individually. We performed an IP with an antibody against the murine hnRNP R.
ORGANISM(S): Mus musculus (Mouse) 
2024-08-22 | PXD043851 | Pride
Hnrnpr Motoneuron Interactome Dda 
UnknownTemporal requirement for SMN in motoneuron development.
Not available
S-EPMC3674802 | biostudies-literature
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