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TranscriptomicsAnalysis of human enteroids and colonoids (3D organoid models from small intestine and colon) exposed to chemotherapy agent 5-fluorouracil (5FU) in a dose-repeated exposure across three doses (10,100 and 1000uM) and sampled at three points (24, 48 and 72h) since initial exposure. Organoids were obtained from healthy human tissues.
ADRs (adverse drug reactions) are one of the main reasons for treatment discontinuation or alterations in dose regimens in clinical settings. Chemotherapy-induced ADRs are common, especially gastrointestinal-induced ones. Within TransQST (transqst.org), one of the main goal is to improve the in vitr...
ORGANISM(S): Homo sapiens 
2021-09-09 | E-MTAB-9134 | biostudies-arrayexpress
ProteomicsCharacterization of the cyclic dipeptide cyclo(His-Pro) in Arabidopsis
The iTSA experiment was designed to map putative protein targets of cyclic dipeptides in Arabidopsis.
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2025-04-17 | MSV000097655 | MassIVE
TranscriptomicsDNA methylation profiling in human Huntington's Disease brain
Despite extensive progress in Huntingtonâ??s Disease (HD) research, very little is known about the association of epigenetic variation and HD pathogenesis in human brain tissues. Moreover, its contribution to the tissue-specific transcriptional regulation of the huntingtin gene (HTT), in which HTT e...
ORGANISM(S): Homo sapiens 
2016-03-11 | E-GEOD-79064 | biostudies-arrayexpress
UnknownRandomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers.
Not available
S-EPMC10497190 | biostudies-literature
UnknownBacille Calmette-Guerin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial.
Not available
S-EPMC11106519 | biostudies-literature
UnknownBacillus Calmette-Guerin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial.
Not available
S-EPMC10500555 | biostudies-literature
UnknownFostamatinib for Hospitalized Adults With COVID-19 and Hypoxemia: A Randomized Clinical Trial.
Not available
S-EPMC11615712 | biostudies-literature
UnknownEffect of Bacille Calmette-Guerin vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination.
Not available
S-EPMC11761716 | biostudies-literature
UnknownBCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial).
Not available
S-EPMC8557250 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
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