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ProteomicsRational in vitro design of a two-phage cocktail against a contemporary Acinetobacter baumannii strain recovered from a burned patient at CHUV
Acinetobacter baumannii is currently a major threat to human health. With the spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains, the development of complementary strategies is needed. A promising complimentary and realistic strategy could be phage therapy, which uses b...
ORGANISM(S): Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 
2025-12-08 | PXD062593 | Pride
A. baumannii Phage cocktail Phage therapy 
TranscriptomicsTranscription profiling of human nevoid basal cell carcinoma syndrome primary fibroblasts with non-sense or miss-sense mutations in the tumor supressor gene PTCH1
Mutations in the tumor suppressor gene PTCH1 are responsible for Gorlin syndrome, or nevoid basal cell carcinoma syndrome (NBCCS). NBCCS causes predisposition to basal cell carcinoma (BCC), the commonest cancer in adult human. In the general population BCC develop almost exclusively in sun-exposed a...
ORGANISM(S): Homo sapiens 
2009-03-19 | E-TABM-549 | biostudies-arrayexpress
UnknownThe circadian oscillator analysed at the single-transcript level.
Not available
S-EPMC7957410 | biostudies-literature
TranscriptomicsTranscription profiling of human xenografted nasopharyngeal carcinoma tumor cell lines and an untransformed diploid fibroblast cell line
The aim of this experiment was to investigate the gene expression profile of two xenografted nasopharyngeal carcinoma tumors - C15 and C17 – which are international reference tools for biological investigations of this type of disease. C15 and C17 transcriptome was profiled by comparison with human...
ORGANISM(S): Homo sapiens 
2007-12-01 | E-TABM-382 | biostudies-arrayexpress
ProteomicsActinomycin targets NPM1c-primed mitochondria in AML
Acute myeloid leukemia (AML) pathogenesis often involves a mutation in the NPM1 nucleolar chaperone, but the bases for its transforming properties and association with favorable outcome remain incompletely understood. Here we demonstrate that an oncogenic mutant form of NPM1 (NPM1c) hampers formatio...
ORGANISM(S): Homo sapiens (Human) 
2021-12-17 | PXD025507 | Pride
Pml Lfq Actinomycin d Mitochondria Npm1c Qexactive Senescence 
UnknownCharacterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl- Current in Vascular Myocytes.
Not available
S-EPMC9699600 | biostudies-literature
ProteomicsExtracellular vesicles proteome from Faecalibacterium duncaniae A2-165 in response to hydrogen peroxyde stress
Faecalibacterium duncaniae A2-165 was incubated in the presence or absence of 440 µM H₂O₂, and extracellular vesicles were isolated from the cell-free supernatant for comparative proteomic analysis limited to protein identification to evaluate the impact of oxidative stress.
ORGANISM(S): Faecalibacterium prausnitzii A2-165 Bacteria 
2026-05-05 | PXD073554 | Pride
Faecalibacterium Proteomic analysis Extracellular vesicles Stress 
TranscriptomicsIGR_CREMEC_CGH_STYDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
UnknownEndometrial receptivity profile in patients with premature progesterone elevation on the day of HCG administration.
Not available
S-EPMC4022194 | biostudies-literature
TranscriptomicsTranscription profiling of human Mo7e cells transduced with control- or p210(BCR-ABL)-GFP viruses
The profiles of transcripts of Mo7e cells transduced with control- or p210(BCR-ABL)-GFP viruses were compared using microarrays to investigate
ORGANISM(S): Homo sapiens 
2007-10-31 | E-TABM-173 | biostudies-arrayexpress
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