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ProteomicsProteomic and functional analysis identifies proteins related to embryonic development in decidua of patients with early recurrent miscarriage
Recurrent miscarriage (RM) is the occurrence of repeated pregnancies that end in miscarriage of the fetus before 20 weeks of gestation. Recurrent miscarriages affect about 1-2% of couples trying to conceive; however, mechanisms leading to this complication are largely unknown. Our previous studies u...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD023849 | Pride
Recurrent miscarriage  tmt  decidua  ipa  embryonic development 
GenomicsLarix decidua
Larix decidua overview
PRJNA74479 | ENA
TranscriptomicsTranscription profiling of human adipose tissue, decidua and placenta from patients with preeclampsia vs. unaffected indviduals reveals dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia
Preeclampsia complicates more than 3% of all pregnancies in the United States and Europe. High-risk populations include women with diabetes, dyslipidemia, thrombotic disorders, hyperhomocysteinemia, hypertension, renal diseases, previous preeclampsia, twin pregnancies, and low socioeconomic status. ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6573 | biostudies-arrayexpress
ProteomicsComparative proteomics analysis of decidua tissues in early recurrent pregnancy loss
The project aimed to determine proteomics changes in decidua from patients suffering from unexplained early recurrent pregnancy loss (RPL) compared to women undergoing elective abortions. Comparative proteomics analysis by label-free data-independent LC-MS/MS was performed on fresh frozen decidua ti...
ORGANISM(S): Homo sapiens (Human) 
2024-06-12 | PXD048340 | Pride
Human Recurrent pregnancy loss Rapigest Progenesis qip Decidua Biomarker Lc-ms/ms 
GenomicsLarix decidua
Larix decidua Microsporocytes Transcriptome
PRJNA624007 | ENA
TranscriptomicsReconstructing the human first trimester fetal-maternal interface using single cell transcriptomics - Smartseq 2 data
To explore the interactions between the range of maternal and fetal placental cell types present, we profiled the transcriptomes of more than 50,000 single cells from matched first trimester samples of maternal blood and decidua, as well as fetal cells from the placenta itself. This part contains RN...
ORGANISM(S): Homo sapiens 
2019-08-21 | E-MTAB-6678 | biostudies-arrayexpress
ProteomicsProteome-defined changes in cellular pathways for decidua and trophoblast tissues associated with location and viability of early-stage pregnancy
A label-free proteome analysis comparing changes in protein profiles of decidualized endometria and trophoblasts among women with different pregnancy outcomes, specifically a viable intrauterine pregnancy (IUP), ectopic pregnancy (EP), or early pregnancy loss (EPL), that identify potential biomarker...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-16 | MSV000088572 | MassIVE
TranscriptomicsExpression data of human decidual NK cells from gravid uteri and NK cells from cycling endometrium
Human NK cells from the decidua basalis of gravid uteri (dNK) and from cycling endometrium (eNK) of women undergoing hysterectomy were isolated and compared by gene expression profiling using Affymetrix microarrays with probes representing ~47,400 transcripts. Substantial differences indicate th...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-20499 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of decidua basalis from women with normal pregnancies or preeclampsia and/or fetal growth restriction
The aim of the study was to compare gene expression profiles in decidua basalis from cases with complicated pregnancies to those from healthy pregnant controls. Cases included pregnant women with preeclampsia (PE) and/or fetal growth restriction (FGR). Decidual tissue was obtained by vacuum suction ...
ORGANISM(S): Homo sapiens 
2007-08-31 | E-MEXP-1050 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Pluripotent Stem Cell-Derived Endometrial Stromal Fibroblasts in Monolayer Differentiation and in Co-culture with Endometrial Epithelial Organoids
H9 Pluripotent Stem Cells (PSC) were differentiated to Endometrial Stromal Fibroblasts (PSC-ESF) in monolayer over the course of 12 days. Gene expression was measured at day 0, day 4, day 8, and day 12 of differentiation. At day 12, PSC-ESF were dissociated from monolayer culture for co-culture with...
ORGANISM(S): Homo sapiens 
2021-05-05 | E-MTAB-10375 | biostudies-arrayexpress
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