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TranscriptomicsGene expression data from MDA-MB231 cells stably transduced with lentiviral vectors encoding a control shRNA (shscramble) or two shRNAs targeting Coco (shco2 and shco4)
Metastatic relapse of breast cancer and other tumor types usually occurs several years after surgical resection of the primary tumor. Early dissemination of tumor cells followed by an extended period of dormancy is thought to explain this prevalent clinical behavior. By using a gain-of-function retr...
ORGANISM(S): Homo sapiens 
2012-08-16 | E-GEOD-28049 | biostudies-arrayexpress
ModelsBegitt2014 - STAT1 cooperative DNA binding - double GAS polymer model
Begitt2014 - STAT1 cooperative DNA binding - double GAS polymer model The importance of STAT1-cooperative DNA binding in type 1 and type 2 interferon signalling has been studies using experimental and modelling approaches. The authors have developed two ODE models to describe STAT1...
2024-09-02 | BIOMD0000000501 | BioModels
ModelsBegitt2014 - STAT1 cooperative DNA binding - single GAS polymer model
Begitt2014 - STAT1 cooperative DNA binding - single GAS polymer model The importance of STAT1-cooperative DNA binding in type 1 and type 2 interferon signalling has been studies using experimental and modelling approaches. The authors have developed two ODE models to describe STAT1...
2024-09-02 | BIOMD0000000500 | BioModels
Manuscript Accepted 
UnknownAnti-hormonal maintenance treatment with the CDK4/6 inhibitor ribociclib after 1st line chemotherapy in hormone receptor positive / HER2 negative metastatic breast cancer: A phase II trial (AMICA).
Not available
S-EPMC10507224 | biostudies-literature
UnknownTreatment and outcome in metastatic lobular breast cancer in the prospective German research platform OPAL.
Not available
S-EPMC10036409 | biostudies-literature
Proteomicsdia-PASEF HeLa dilution series 0.2ng - 200ng on Bruker timsTOF Pro 2
Different sample preparation methods were tested for HeLa proteome analysis. A sample obtained using sodium deoxycholate-based lysis allowed identification of the highest number of proteins. For this sample, a dilution series was acquired in triplicates ranging from 0.2ng to 200ng. All measurements ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-20 | PXD029836 | Pride
Dia-pasef diapasef dia-nn hela 
UnknownHead-to-head comparison of palbociclib and ribociclib in first-line treatment of HR-positive/HER2-negative metastatic breast cancer with real-world data from the OPAL registry.
Not available
S-EPMC11887017 | biostudies-literature
UnknownA multicentre, randomised, double-blind, phase II study to evaluate the tolerability of an induction dose escalation of everolimus in patients with metastatic breast cancer (DESIREE).
Not available
S-EPMC9832733 | biostudies-literature
ProteomicsHomeostatic and Interferon-induced gene expression represent different states of promoter-associated transcription factor ISGF3
Host defense by the innate immune system requires the establishment of antimicrobial states allowing cells to cope with microorganisms before the onset of the adaptive immune response. Interferons (IFN) are of vital importance in the establishment of cell-autonomous antimicrobial immunity. Speed is...
ORGANISM(S): Mus Musculus 
2019-07-15 | PXD013251 | panorama
ProteomicsDIA proteomics on mouse tissue to investigate the GAPDH redox switch
The glycolytic enzyme GAPDH is equipped with a redox switch that rapidly and reversibly inactivates the enzyme in the presence of hydrogen peroxide. The physiological implications of the redox switch were investigated in C57BL/6NTac wildtype and GAPDH(T175A) knock-in mice generated by CRISPR/Cas9 ge...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-10 | PXD040620 | Pride
Heart Tissue Mus musculus Kidney Gapdh Dia-pasef Mouse 
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