Sort   by:  
 Page size 
TranscriptomicsHuman Splice Junction Arrays of Parkinson's Patients Leukocytes mRNA Pre- and Post-Deep Brain Stimulation
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide and the first involving motor symptoms. Deep brain stimulation (DBS) neurosurgery treatment through electrodes implanted to the subthalamic nucleus (STN) improves dramatically the debilitating motor symptoms of th...
ORGANISM(S): Homo sapiens 
2015-05-22 | E-GEOD-37591 | biostudies-arrayexpress
TranscriptomicsExpression data from advanced Parkinson's disease (PD) patients leukocytes - prior to and following deep brain stimulation (DBS) treatment in on and off stimulation conditions, and matched healthy control (HC) subjects
Sub-thalamic deep brain stimulation (DBS) reversibly modulates ParkinsonM-bM-^@M-^Ys disease (PD) motor symptoms, providing an unusual opportunity to compare leukocyte transcripts in the same subjects before and after neurosurgery and after disconnecting the stimulus (ON-and OFF-stimulus). Here, we ...
ORGANISM(S): Homo sapiens 
2012-01-09 | E-GEOD-23676 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the small RNA transcriptome of blood leukocytes from Parkinson's disease patients prior to and following deep brain stimulation (DBS) and as compared with healthy control volunteers
We report the application of small RNA sequencing technology for high-throughput profiling of microRNA molecules (miRNAs) in blood leukocytes of Parkinson's Disease (PD) patients. Expression changes which may contribute to PD pathogenesis and reaction to treatment were identified in RNA preparations...
ORGANISM(S): Homo sapiens 
2013-11-21 | E-GEOD-40915 | biostudies-arrayexpress
TranscriptomicsWhole-transcriptome high-throughput RNA sequencing of blood leukocytes from Parkinson's disease human patients pre- and post-deep brain stimulation
The given data set is the first deep sequencing transcriptome-wide data set of human Parkinson's disease (PD) patients RNA. The data set was produced from blood leukocytes of PD patients, from the same patients following deep brain stimulation (DBS), and from matched healthy control volunteers. Post...
ORGANISM(S): Homo sapiens 
2014-07-16 | E-GEOD-42608 | biostudies-arrayexpress
TranscriptomicsHigh-frequency stimulation of the ventrolateral thalamus regulates gene expression in hippocampus, motor cortex and caudate-putamen
Transcriptional profiling of rat hippocampus comparing rats subjected to chronic (1 hour daily during 14 days) vetrolateral thalamus stimulation (DBS group) with sham operated rats (with electrode placement but without stimulation) and with naive rats. Three-condition experiment, DBS, sham and nai...
ORGANISM(S): Rattus norvegicus 
2011-06-30 | E-GEOD-25860 | biostudies-arrayexpress
UnknownAcute effects of adaptive Deep Brain Stimulation in Parkinson's disease.
Not available
S-EPMC7116216 | biostudies-literature
UnknownA brain network for deep brain stimulation induced cognitive decline in Parkinson's disease.
Not available
S-EPMC9129093 | biostudies-literature
UnknownOscillatory network markers of subcallosal cingulate deep brain stimulation for depression.
Not available
S-EPMC10947774 | biostudies-literature
UnknownNeurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions.
Not available
S-EPMC10629774 | biostudies-literature
UnknownDeep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.
Not available
S-EPMC11919902 | biostudies-literature
Sort   by:  
 Page size