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ProteomicsBistability in the Rac1, PAK and RhoA signalling network is a feature of cell motility.
Dynamic interactions between RhoA and Rac1, members of the Rho small GTPase family, play a vital role in the control of cell migration. Using predictive mathematical modelling and experimental validation in MDA-MB-231 mesenchymal breast cancer cells, we show that Rac1 and RhoA interactions via the P...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080751 | MassIVE
ProteomicsA phosphoproteomic and transcriptomic analysis of carnosine’s action on signaling in glioblastoma U87-MG cells
Previous studies demonstrated that carnosine affects signaling molecules of different pathways in a number of experimental models. However, the primary targets of carnosine are still unknown and its effect on complex signal transduction has not been revealed. This is especially the case for pathways...
ORGANISM(S): Homo sapiens 
2019-11-30 | E-MTAB-6455 | biostudies-arrayexpress
UnknownSerum Vitamin D Concentration Is Lower in Patients with Tinnitus: A Meta-Analysis of Observational Studies.
Not available
S-EPMC10047354 | biostudies-literature
UnknownSpike-specific humoral and cellular immune responses after COVID-19 mRNA vaccination in patients with cirrhosis: A prospective single center study.
Not available
S-EPMC9575378 | biostudies-literature
UnknownCirrhosis and rapid virological response to peginterferon plus ribavirin determine treatment outcome in HCV-1 IL28B rs12979860 CC patients.
Not available
S-EPMC3722882 | biostudies-literature
UnknownRelationship Between Dimensionality and Convergence of Optimization Algorithms: A Comparison Between Data-Driven Normalization and Scaling Factor-Based Methods Using PEPSSBI.
Not available
S-EPMC9446379 | biostudies-literature
UnknownSofosbuvir for the treatment of chronic hepatitis C: between current evidence and future perspectives.
Not available
S-EPMC4010630 | biostudies-literature
UnknownAccuracy of Transient Elastography in Assessing Fibrosis at Diagnosis in Naive Patients With Primary Biliary Cholangitis: A Dual Cut-Off Approach.
Not available
S-EPMC8518641 | biostudies-literature
ProteomicsDHODH is a synthetic-lethal vulnerability in BCOR-deficient acute myeloid leukemia
Acute Myeloid Leukemia (AML) remains challenging to treat, especially in cases with mutations in the BCL-6 co-repressor (BCOR), which are associated with poor prognosis and chemo-resistance. In this study, we reveal a synthetic lethal interaction between BCOR and dihydroorotate dehydrogenase (DHODH)...
ORGANISM(S): Homo sapiens (Human) 
2026-09-24 | PXD062779 | Pride
Acute myeloid leukemia Bcor Am Bcl-6 co-repressor 
UnknownPredicting Hepatocellular Carcinoma Risk in Patients with Chronic HCV Infection and a Sustained Virological Response to Direct-Acting Antivirals.
Not available
S-EPMC8254542 | biostudies-literature
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