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RUNX1 is a transcription factor functioning both as an oncogene and a tumor suppressor in breast cancer. RUNX1 alters chromatin structure in cooperation with chromatin modifier and remodeling enzymes. In this study, we examined the relationship between RUNX1-mediated transcription and genome organiz...
ORGANISM(S): Homo sapiens 
This submission contains the proteomic data from the paper “Culinary diversity in early modern Brazil revealed by residues analysis of ceramic artefacts” by Di Muro et al.. In this paper the culinary use of ceramic during the late 19th and early 20th century in Brazil is investigated through biomole...
ORGANISM(S): unidentified blank sample 
2026-06-15 | PXD068877 | Pride
The packaging of DNA into chromatin plays an important role in transcriptional regulation and nuclear processes. Brahma related gene-1 SMARCA4 (also known as BRG1), the essential ATPase subunit of the mammalian SWI/SNF chromatin remodeling complex, uses the energy from ATP hydrolysis to disrupt nucl...
ORGANISM(S): Homo sapiens 
Background: Higher-order chromatin structure is often perturbed in cancer and other pathological states. Although several genetic and epigenetic differences have been charted between normal and breast cancer tissues, changes in higher-order chromatin organization during tumorigenesis have not been f...
ORGANISM(S): Homo sapiens 
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